精神分裂症患者的神经额叶体征与神经心理学缺陷

Neurological frontal signs and neuropsychological deficits in schizophrenic patients.

作者信息

Cuesta M J, Peralta V, de Leon J

机构信息

Psychiatric Unit I, Virgen del Camino Hospital, Pamplona, Spain.

出版信息

Schizophr Res. 1996 May;20(1-2):15-20. doi: 10.1016/0920-9964(95)00110-7.

DOI:10.1016/0920-9964(95)00110-7

PMID:8794489

Abstract

A higher prevalence of neurological signs (NS) has been described in schizophrenic patients when compared with controls or patients with other mental illnesses. This study, which includes a sample of 66 DSM-IIIR schizophrenics, was designed to assess the relationship between 7 frontal neurologic signs described by Luria and cognitive disturbances measured by an exhaustive neuropsychological battery. There was a statistically significant relationships between the frontal signs and the cognitive deficits (mean shared variance was 22%) which persisted after correcting for the influence of age, education, and duration of illness.

摘要

与对照组或患有其他精神疾病的患者相比，精神分裂症患者中神经体征（NS）的患病率更高。本研究纳入了66例DSM-IIIR精神分裂症患者样本，旨在评估Luria描述的7种额叶神经体征与通过全面神经心理测验所测量的认知障碍之间的关系。额叶体征与认知缺陷之间存在统计学上的显著关系（平均共同方差为22%），在校正年龄、教育程度和病程的影响后，这种关系依然存在。