Tiffin P A, MacEwen C J, Craig E A, Clayton G
Department of Ophthalmology, Ninewells Hospital and Medical School, Dundee, UK.
Eye (Lond). 1996;10 ( Pt 3):377-84. doi: 10.1038/eye.1996.77.
There have been few studies primarily concerned with the relative frequencies, aetiologies and prognoses of ocular motor palsies. Those published have emanated largely from neurological tertiary referral centres rather than primary ophthalmology departments. We have performed a retrospective study of all patients with acquired III, IV or VI cranial nerve palsy who were seen in the orthoptic department at Ninewells Hospital, Dundee, over the 9 year period from 1984 to 1992. A total of 165 cases were identified. VI nerve palsies accounted for the majority of patients (57%), with IV nerve palsies (21%) occurring more frequently than III nerve palsies (17%) and multiple palsies (5%). Thirty-five per cent of cases were of unknown aetiology and 32% of vascular aetiology. The incidence of sinister pathology-neoplasia (2%) and aneurysm (1%)-was surprisingly low. Fifty-seven per cent of all patients made a total recovery (in a median time of 3 months) and 80% made at least a partial recovery. The results are contrasted with those of previous studies and the value of associated symptoms and of further investigation in the assessment of these patients is discussed.
很少有研究主要关注眼球运动麻痹的相对频率、病因和预后。已发表的研究大多来自神经科三级转诊中心，而非眼科初级科室。我们对1984年至1992年这9年间在邓迪九井医院斜视矫正科就诊的所有后天性动眼神经、滑车神经或展神经麻痹患者进行了一项回顾性研究。共确定了165例病例。展神经麻痹患者占大多数（57%），滑车神经麻痹（21%）比动眼神经麻痹（17%）和多条神经麻痹（5%）更常见。35%的病例病因不明，32%为血管性病因。恶性病变（肿瘤，2%）和动脉瘤（1%）的发生率出奇地低。所有患者中有57%完全康复（中位时间为3个月），80%至少部分康复。将结果与先前研究的结果进行了对比，并讨论了相关症状及进一步检查在评估这些患者中的价值。
