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伏格特-小柳-原田综合征:与1型自身免疫性多腺体综合征的关联。

The Vogt-Koyanagi-Harada syndrome: association with autoimmune polyglandular syndrome type 1.

作者信息

Jovic N S, Nesovic M, Vranjesevic D N, Ciric J, Marinkovic D M, Bonaci B

机构信息

Department of Neurology and Psychiatry for Children and Youth, Belgrade, Yugoslavia.

出版信息

Postgrad Med J. 1996 Aug;72(850):495-7. doi: 10.1136/pgmj.72.850.495.

Abstract

We describe a young woman with primary adrenal insufficiency, hypoparathyroidism (autoimmune polyglandular syndrome type 1), Graves disease, vitiligo, and alopecia universalis. Five years after the diagnosis, she presented with recurrent ophthalmological and neurological disorders as features of Vogt-Koyanagi-Harada syndrome. A marked therapeutic response was noted on systemic high-dose corticosteroid treatment. To the best of our knowledge, such a spectre of autoimmune diseases has not been reported previously.

摘要

我们描述了一位患有原发性肾上腺功能不全、甲状旁腺功能减退(1型自身免疫性多腺体综合征)、格雷夫斯病、白癜风和全秃的年轻女性。诊断五年后,她出现了复发性眼科和神经疾病,表现为Vogt-小柳-原田综合征。全身大剂量皮质类固醇治疗后有明显的治疗反应。据我们所知,此前尚未报道过如此一系列的自身免疫性疾病。

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