Rappaport M, Hall K, Hopkins K, Belleza T, Berrol S, Reynolds G
Arch Phys Med Rehabil. 1977 Aug;58(8):333-8.
Various measures of evoked brain potential abnormality (EPA) were correlated with disability ratings (DR) for 35 brain-damaged patients. EPA data consisted of judgements of abnormality of ipsilateral, contralateral and bilateral responses to auditory and visual stimuli reflecting activity in the brain stem, subcortex and cortex. DR data were obtained from a scale developed for this study to quantize and categorize patients with a wide range of disabilities from coma to normal functioning. EPA scores based on visual and auditory cortical responses showed significantly positive correlations with degree of disability. Visual response correlation was .49, auditory .38 and combined visual and auditory .51. It was concluded that EPA measures can reflect disability independently of clinical information. They are useful in assessing brain function in general and, specifically, in assessing impairment of sensory function. The evoked potential technique was particularly useful in patients who were not able to participate fully in their own examination. There were indications that the technique may also be valuable in monitoring progress and in predicting clinical outcome in brain-damaged patients.
对35名脑损伤患者的诱发脑电位异常（EPA）的各种测量指标与残疾评定（DR）进行了相关性分析。EPA数据包括对听觉和视觉刺激的同侧、对侧及双侧反应异常的判断，这些反应反映了脑干、皮层下和皮层的活动。DR数据来自为本研究制定的一个量表，该量表用于对从昏迷到功能正常的广泛残疾患者进行量化和分类。基于视觉和听觉皮层反应的EPA评分与残疾程度呈显著正相关。视觉反应的相关性为0.49，听觉为0.38，视觉和听觉综合为0.51。得出的结论是，EPA测量可以独立于临床信息反映残疾情况。它们总体上有助于评估脑功能，特别是在评估感觉功能损害方面。诱发电位技术在无法充分参与自身检查的患者中特别有用。有迹象表明，该技术在监测脑损伤患者的病情进展和预测临床结果方面也可能有价值。
