d'Onofrio F, Salvia S, Petretta V, Bonavita V, Rodriguez G, Tedeschi G
Institute of Neurological Sciences, II University of Naples, Italy.
Acta Neurol Scand. 1996 May;93(5):336-45. doi: 10.1111/j.1600-0404.1996.tb00006.x.
The value of quantitative electroencephalography (q-EEG) in the differential diagnosis of multi-infarct dementia (MID) and dementia of Alzheimer's type (DAT) is controversial. To evaluate the possible diagnostic role of q-EEG in these two conditions we studied 18 healthy adults, 16 healthy elderly (HE), 29 DAT patients and 45 MID patients. MID patients showed a significant increase of delta activity on the occipital regions, a significant widespread increase of theta activity, a significant widespread decrease of alpha activity. DAT patients showed a significant widespread increase of delta and theta activity, a significant widespread decrease of alpha activity. Spectral profile analysis showed an asymptotic exponential peak frequency at 4.33 HZ, and the disappearance of dominant activity in DAT patients; a 1 Hz decrease of peak frequency with a preserved normal profile in MID patients. We conclude that q-EEG is a useful ancillary test to differentiate MID from DAT.
定量脑电图（q - EEG）在多梗死性痴呆（MID）和阿尔茨海默型痴呆（DAT）鉴别诊断中的价值存在争议。为评估q - EEG在这两种病症中可能的诊断作用，我们研究了18名健康成年人、16名健康老年人（HE）、29名DAT患者和45名MID患者。MID患者枕区δ活动显著增加，θ活动广泛显著增加，α活动广泛显著减少。DAT患者δ和θ活动广泛显著增加，α活动广泛显著减少。频谱分析显示，DAT患者的渐近指数峰值频率为4.33赫兹，且主导活动消失；MID患者峰值频率降低1赫兹，仍保留正常频谱形态。我们得出结论，q - EEG是鉴别MID和DAT的有用辅助检查。
