Lao T T, Lee C P, Mak W P
Department of Obstetrics and Gynaecology, University of Hong Kong, Tsan Yuk Hospital, Hong Kong.
Eur J Obstet Gynecol Reprod Biol. 1996 Jan;64(1):7-10. doi: 10.1016/0301-2115(95)02242-2.
To determine whether the maternal haemoglobin and iron stores of non-anaemic mothers (haemoglobin > or = 10 g/dl) who developed postpartum anaemia were lower compared to mothers who did not develop postpartum anaemia.
A prospective study was conducted in a teaching hospital on 467 low-risk mothers recruited from the antenatal clinic over a 3-month period, who were given only low dose iron supplement and delivered in the same hospital. Blood was drawn at 28-30 weeks for the measurement of haemoglobin, mean cell volume, serum ferritin, serum iron and total iron binding capacity. These results were compared between mothers with a postpartum day 3 haemoglobin of > or = 10 g/dl and those < 10 g/dl. Statistical analysis was performed with parametric and non-parametric methods as appropriate.
Mothers with postpartum anaemia had a higher incidence of postpartum haemorrhage (19.6% vs. 3.9%, P < 0.001) as well as heavier mean intrapartum blood loss (444 ml vs. 304 ml, P < 0.001), but there was no difference in the haemoglobin, mean cell volume, serum ferritin, serum iron and total iron binding capacity.
In mothers without antenatal anaemia, the development of postpartum anaemia is not related to the maternal iron status in the third trimester.