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缺铁性贫血中的血清铁蛋白(作者译)

[Serum ferritin in iron deficiency anaemia (author's transl)].

作者信息

Oertel J, Gerhartz H

出版信息

Dtsch Med Wochenschr. 1977 Aug 12;102(32):1147-50. doi: 10.1055/s-0028-1105475.

Abstract

Red cell indices, plasma iron, total iron-binding capacity and serum ferritin levels were measured in 73 patients with iron deficiency anaemia. There was decreased plasma iron and MCHC with an increased total iron-binding capacity in 38 patients (type I iron deficiency anaemia). There was no hypochromia in 18 patients with decreased plasma iron and normal total iron-binding capacity; haemoglobin concentration was higher than 90 g/l (type II). Normal MCHC, plasma iron and total iron-binding capacity were found in 17 patients with haemoglobin values higher than 105 g/l (type III). Serum ferritin measurements were made by the immunoradiometric assay. The ferritin concentration was less than 40 micron/l in 66 patients with iron deficiency anaemia. The test proved reliable in diagnosing mild iron deficiency anaemia (types II and III) without bone marrow aspiration.

摘要

对73例缺铁性贫血患者进行了红细胞指数、血浆铁、总铁结合力和血清铁蛋白水平的测定。38例患者(I型缺铁性贫血)血浆铁和平均红细胞血红蛋白浓度降低,总铁结合力升高。18例血浆铁降低、总铁结合力正常的患者无低色素血症;血红蛋白浓度高于90g/l(II型)。17例血红蛋白值高于105g/l的患者平均红细胞血红蛋白浓度、血浆铁和总铁结合力正常(III型)。血清铁蛋白测定采用免疫放射分析法。66例缺铁性贫血患者的铁蛋白浓度低于40μg/l。该试验在不进行骨髓穿刺的情况下诊断轻度缺铁性贫血(II型和III型)时被证明是可靠的。

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