Leen E J, Rees P J, Sanderson J D, Wilkinson M L, Filipe M I
Department of Histopathology, Guy's Hospital, London.
Gut. 1996 Feb;38(2):299-301. doi: 10.1136/gut.38.2.299.
A case is presented of Churg-Strauss syndrome in a young man in whom the definitive diagnostic procedure was a full thickness sigmoidoscopic rectal biopsy, with submucosal sampling. Gastrointestinal changes in Churg-Strauss syndrome, a rare systemic illness characterised by asthma, blood and tissue eosinophilia, vasculitis, and granulomatous inflammation are common but poorly reported. The endoscopic and histopathological features of a case are described and emphasise the potential value of a limited sigmoidoscopy in establishing the diagnosis, when lower gastrointestinal symptoms are present.
本文报告了一例发生在一名年轻男性身上的变应性肉芽肿性血管炎，其中确诊的诊断方法是进行全层乙状结肠镜直肠活检及黏膜下采样。变应性肉芽肿性血管炎是一种罕见的全身性疾病，其特征为哮喘、血液和组织嗜酸性粒细胞增多、血管炎和肉芽肿性炎症，胃肠道改变很常见，但报道较少。本文描述了一例的内镜和组织病理学特征，并强调当下消化道出现症状时，有限的乙状结肠镜检查在确立诊断方面的潜在价值。
