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胰岛素对大鼠脂肪细胞和比目鱼肌中[45Ca]钙洗脱的影响。

The effect of insulin on the washout of [45Ca]calcium from adipocytes and soleus muscle of the rat.

作者信息

Clausen T, Martin B R

出版信息

Biochem J. 1977 Apr 15;164(1):251-5. doi: 10.1042/bj1640251.

DOI:10.1042/bj1640251
PMID:880231
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1164780/
Abstract

Insulin stimulates the washout of 45Ca from preloaded isolated fat-cells, whole epididymal fat-pads and isolated soleus muscles of the rat. This effect occurs within 10 min after the addition of the hormone, and it can be detected at concentrations down to those measured in rat plasma. When K+ is omitted from the washout medium, the effect on soleus muscles is more pronounced and increases with the time of exposure.

摘要

胰岛素可刺激预先加载钙的大鼠分离脂肪细胞、附睾脂肪垫及分离的比目鱼肌中45Ca的流出。该效应在添加激素后10分钟内出现，且在低至大鼠血浆中测得的浓度时即可检测到。当冲洗培养基中不含K+时，对比目鱼肌的效应更明显，且随暴露时间延长而增强。

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本文引用的文献

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THE BINDING OF CALCIUM ION BY THE HUMAN ERYTHROCYTE MEMBRANE.钙离子与人红细胞膜的结合
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The effect of cyanide on the efflux of calcium from squid axons.氰化物对鱿鱼轴突钙外流的影响。
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The dependence of calcium efflux from cardiac muscle on temperature and external ion composition.心肌中钙外流对温度和细胞外离子成分的依赖性。
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The relationship between the transport of glucose and cations across cell membranes in isolated tissues. VI. The effect of insulin, ouabain, and metabolic inhibitors on the transport of 3-O-methylglucose and glucose in rat soleus muscles.离体组织中葡萄糖与阳离子跨细胞膜转运的关系。VI. 胰岛素、哇巴因和代谢抑制剂对大鼠比目鱼肌中3-O-甲基葡萄糖和葡萄糖转运的影响。
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The efflux of calcium from single crab and barnacle muscle fibres.单个螃蟹和藤壶肌纤维中钙的外流。
J Physiol. 1972 Jun;223(3):735-55. doi: 10.1113/jphysiol.1972.sp009872.
6
The relationship between the transport of glucose and cations across cell membranes in isolated tissues. VII. The effects of extracellular Na + and K + on the transport of 3-O-methylglucose and glucose in rat soleus muscle.离体组织中葡萄糖与阳离子跨细胞膜转运的关系。VII. 细胞外Na⁺和K⁺对大鼠比目鱼肌中3 - O - 甲基葡萄糖和葡萄糖转运的影响。
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The role of ions in the hormonal control of adipose tissue.
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The relationship between calcium exchange and enzyme secretion in the isolated rat pancreas.离体大鼠胰腺中钙交换与酶分泌之间的关系。
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A procedure for measurement of distribution spaces in isolated fat cells.一种测量分离脂肪细胞中分布空间的方法。
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Calcium and magnesium ions as effectors of adipose-tissue pyruvate dehydrogenase phosphate phosphatase.钙和镁离子作为脂肪组织丙酮酸脱氢酶磷酸磷酸酶的效应物。
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