来自再生大鼠肝脏的糙面内质网制剂中的UDP-N-乙酰葡糖胺-天冬酰胺序列N-乙酰-β-D-葡糖胺基转移酶活性
The UDP-N-acetylglucosamine-asparagine-sequon N-acetyl-beta-D-glucosaminyltransferase activity in preparations of rough endoplasmic reticulum from regenerating rat liver.
作者信息
Khalkhali Z, Serafini-Cessi F, Marshall R D
出版信息
Biochem J. 1977 Apr 15;164(1):257-61. doi: 10.1042/bj1640257.
Abstract
The UDP-N-acetylglucosamine-asparagine-sequon N-acetylglucosaminyltransferase activity in preparations of rough endoplasmic reticulum from rat liver is less than 1% of that in preparations from rabbit liver. The activity of the enzyme is increased about 20-fold in preparations from regenerating rat liver within 48h after partial hepatectomy. A smaller, but still marked, increase (8-10-fold) occurs in preparations of rough endoplasmic reticulum from sham-operated rats.
摘要
大鼠肝脏粗面内质网制剂中UDP-N-乙酰葡糖胺-天冬酰胺序列N-乙酰葡糖胺基转移酶的活性不到兔肝脏制剂中该酶活性的1%。在部分肝切除术后48小时内，再生大鼠肝脏制剂中该酶的活性增加了约20倍。假手术大鼠的粗面内质网制剂中也出现了较小但仍很显著的增加（8-10倍）。
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