Kinnunen T, Doherty K, Militello F S, Garvey A J
Department of Oral Health and Epidemiology, School of Dental Medicine, Harvard University, Boston, Massachusetts, USA.
J Consult Clin Psychol. 1996 Aug;64(4):791-8. doi: 10.1037//0022-006x.64.4.791.
Previous research has linked depression to difficulties in smoking cessation. The authors followed 269 smokers who attempted to quit smoking for 3 months. Participants were given nicotine gum (2 or 4 mg) or placebo gum and brief counseling. The study found that 34% of the smokers met the criterion for current depression using the Center for Epidemiological Studies Depression Scale. Depressed smokers relapsed significantly earlier than the nondepressed. Nicotine gum was significantly more effective than placebo gum among all smokers. The benefits of nicotine gum were particularly apparent among the depressed. Only 12.5% of depressed smokers quit successfully with placebo gum for 3 months, whereas 29.5% quit with nicotine gum. Depressed smokers reported more stress, less coping resources, more physical and psychological symptoms, and more frequent smoking in the presence of negative affect than did the nondepressed.
先前的研究已将抑郁症与戒烟困难联系起来。作者对269名试图戒烟3个月的吸烟者进行了跟踪。参与者被给予尼古丁口香糖（2毫克或4毫克）或安慰剂口香糖，并接受简短咨询。研究发现，使用流行病学研究中心抑郁量表，34%的吸烟者符合当前抑郁症的标准。抑郁的吸烟者比非抑郁者复发得更早。在所有吸烟者中，尼古丁口香糖比安慰剂口香糖显著更有效。尼古丁口香糖的益处在抑郁者中尤为明显。使用安慰剂口香糖3个月后，只有12.5%的抑郁吸烟者成功戒烟，而使用尼古丁口香糖的这一比例为29.5%。与非抑郁者相比，抑郁的吸烟者报告有更多压力、更少应对资源、更多身体和心理症状，并且在出现负面情绪时吸烟更频繁。
