Lord J M
Department of Biological Sciences, University of Warwick, Coventry CV4 7AL, UK.
Curr Biol. 1996 Sep 1;6(9):1067-9. doi: 10.1016/s0960-9822(02)70666-0.
Newly synthesized proteins that fail to fold or assemble properly in the endoplasmic reticulum are degraded. Recent work on several endoplasmic reticulum membrane proteins has shown that the cytosolic proteasome plays a role in their degradation.
在内质网中未能正确折叠或组装的新合成蛋白质会被降解。最近对几种内质网膜蛋白的研究表明,胞质蛋白酶体在其降解过程中发挥作用。