Rodríguez E, Díaz C
Department of Analytical Chemistry, Nutrition and Food Science, University of La Laguna, Spain.
J Trace Elem Med Biol. 1995 Dec;9(4):200-9. doi: 10.1016/s0946-672x(11)80025-8.
Urinary Fe, Cu and Zn levels were determined in healthy people from S/C de Tenerife. Males showed higher (p < 0.01) urinary levels (micrograms/L and microgram per day) of Zn than females. However, females had higher daily urinary Fe and Cu excretions per kg of body weight (p < 0.05) than males. Urinary metal concentration, expressed as mg metal per g CT, better reflects daily excretion. Urinary levels of Zn and Cu were within the reference values, but the urinary levels of Fe were lower than that in most of the published data. An increase in daily Fe, Cu and Zn excretion (micrograms per day) with age up to 30 years was observed. An increase with weight and height was also observed. Concentrations and excretions of Zn were significantly (p < 0.015) lower when the urinary pH was above 7. With respect to the frequency of consumption of rich protein food, rich fiber food, coffee, tobacco, or alcohol, only significantly (p = 0.015) higher Zn concentrations and higher (p = 0.091) excretions were found in people that consume alcohol more than 3 times a week. A significant depletion of urinary Zn and Cu concentration and Fe excretion was found in the subjects who usually did physical exercise. Positive intermetallic correlations among the concentrations and excretions of the metals investigated were observed.
测定了特内里费岛圣克鲁斯健康人群的尿铁、铜和锌水平。男性的尿锌水平（微克/升和微克/天）高于女性（p < 0.01）。然而，女性每千克体重的每日尿铁和铜排泄量高于男性（p < 0.05）。以每克肌酐中金属毫克数表示的尿金属浓度能更好地反映每日排泄量。尿锌和铜水平在参考值范围内，但尿铁水平低于大多数已发表数据中的水平。观察到在30岁之前，每日铁、铜和锌排泄量（微克/天）随年龄增加而增加。还观察到随体重和身高增加。当尿pH值高于7时，锌的浓度和排泄量显著降低（p < 0.015）。关于富含蛋白质食物、富含纤维食物、咖啡、烟草或酒精的消费频率，仅在每周饮酒超过3次的人群中发现锌浓度显著升高（p = 0.015）且排泄量升高（p = 0.091）。在经常进行体育锻炼的受试者中发现尿锌和铜浓度以及铁排泄量显著减少。在所研究的金属浓度和排泄量之间观察到金属间的正相关关系。
