Reina M A, López-García A, Dittmann M, de Andrés J A
Servicio de Anestesiología y Reanimación, Hospital General de Móstoles, Madrid.
Rev Esp Anestesiol Reanim. 1996 Apr;43(4):130-4.
In recent years several studies have raised questions about the anatomy of the human dura mater. Our objective has therefore been to examine its tridimensional structure with the aid of the scanning electron microscope.
Samples were taken from 4 human cadavers (70, 72, 77 and 78 years old) between 8 and 12 hours after death. After fixing in glutaraldehyde phosphate buffer, dehydration in acetone and elimination of the acetone at the critical point, treatment with carbon and metallization with gold, the external and internal surfaces were examined.
The external, or epidural, surface of the dura mater is made up of thin collagen fibers joined in bands running in different directions. The outer surface and lower layers of the dura contain elastic, interwoven fibers surpassing 2 microns in diameter. The inner surface, which is smooth and glossy, is formed of thin ribbons of arachnoids that are fused and tightly attached to the structure of the dura mater.
The outer surface of the dura mater consists mainly of collagen fibers which alone or in groups run in different directions: longitudinally, horizontally or obliquely, depending on the are studied. These findings contradict the classical descriptions of the dura mater as having parallel, longitudinally placed collagen fibers in the tangential plane.
近年来，多项研究对人类硬脑膜的解剖结构提出了疑问。因此，我们的目标是借助扫描电子显微镜研究其三维结构。
从4具人类尸体（年龄分别为70岁、72岁、77岁和78岁）死亡后8至12小时取材。在磷酸缓冲戊二醛中固定、丙酮脱水并在临界点去除丙酮、进行碳处理和金镀膜后，检查其内外表面。
硬脑膜的外表面，即硬膜外表面，由细胶原纤维组成，这些纤维以束状形式连接，呈不同方向排列。硬脑膜的外表面和下层含有弹性的、相互交织的纤维，直径超过2微米。光滑有光泽的内表面由蛛网膜的细带形成，这些细带融合并紧密附着于硬脑膜结构。
硬脑膜的外表面主要由胶原纤维组成，这些纤维单独或成组地沿不同方向排列：纵向、横向或斜向，具体取决于所研究的区域。这些发现与传统上对硬脑膜的描述相矛盾，传统描述认为在切面上硬脑膜具有平行的、纵向排列的胶原纤维。
