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固定性狼疮手部畸形及其手术矫正

The fixed lupus hand deformity and its surgical correction.

作者信息

Evans J A, Hastings D E, Urowitz M B

出版信息

J Rheumatol. 1977 Summer;4(2):170-5.

PMID:881693
Abstract

In a prospective study of 125 patients with SLE, three females developed fixed hand deformities. All had arthritis for more than 10 years, and had been treated with a mean daily dose of 15 mg of prednisone. The hand deformities consisted of irreducible metacarpophalangeal (MCP) subluxation and/or dislocation without erosion or destruction of the MCP joints, resulting in hyperflexion of the fingers in the palm. Two patients had dislocation of the carpometacarpal joints in both hands. On patient developed reducible swan-neck deformities in the second to fifth fingers of both hands and a second patient developed Boutonniere deformities in two fingers of one hand and clinodactyly of both fifth fingers. Because the deformity at the MCP joints resulted from soft tissue contractures in the intrinsics and long flexors, and because the cartilage of the MCP joint was preserved, a joint replacement was not considered. Metacarpal osteotomy and shortening was performed to decompress the contracted soft tissues. At follow-up (18-96 months), the hands remained corrected and all patients were able to perform normal activities.

摘要

在一项对125例系统性红斑狼疮患者的前瞻性研究中,三名女性出现了固定性手部畸形。她们都患有关节炎超过10年,平均每日服用15毫克泼尼松进行治疗。手部畸形包括掌指关节(MCP)不可复位的半脱位和/或脱位,而MCP关节无侵蚀或破坏,导致手指在手掌内过度屈曲。两名患者双手的腕掌关节脱位。一名患者双手第二至五指出现可复位的天鹅颈畸形,另一名患者一只手的两个手指出现纽扣花样畸形,双手第五指出现尺偏畸形。由于MCP关节处的畸形是由内在肌和长屈肌的软组织挛缩引起的,且MCP关节的软骨得以保留,因此未考虑进行关节置换。进行了掌骨截骨术和缩短术以松解挛缩的软组织。在随访(18 - 96个月)时,手部畸形得到矫正,所有患者都能够进行正常活动。

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