Heng M K, Barratt-Boyes B, Agnew T M, Brandt P W, Kerr A R, Graham K J
J Thorac Cardiovasc Surg. 1977 Aug;74(2):230-7.
The results of valve replacement with a stent-mounted antibiotic-treated aortic allograft valve are reported in 129 patients with isolated mitral valve disease. Of these patients, 70 per cent were in N.Y.H.A. Class IV. The hospital mortality rate was 3.9 percent. The cumulative complication-free rate at 5 years was only 37 percent as 21 percent died late, a further 15 percent were alive following reoperation, 4 percent had an embolic episode, 4 percent were alive with important incompetence, and 20 percent had unimportant incompetence. Proved valve failure was due mainly to detachment of the aortic wall remnant of the valve from the pillar of the rigid metal stent (16 percent incidence at 5 years) and methods for preventing this complication are discussed. Because of these complications the use of this device in the mitral position has been discontinued.
129例单纯二尖瓣疾病患者接受了带支架的经抗生素处理的主动脉同种异体移植瓣膜置换术，报告了其结果。这些患者中，70%为纽约心脏协会（NYHA）心功能IV级。医院死亡率为3.9%。5年时累积无并发症率仅为37%，因为21%患者晚期死亡，另有15%患者再次手术后存活，4%发生栓塞事件，4%患者存在严重瓣膜关闭不全存活，20%存在轻度瓣膜关闭不全。经证实的瓣膜失败主要是由于瓣膜的主动脉壁残余部分与刚性金属支架柱分离（5年发生率为16%），并讨论了预防该并发症的方法。由于这些并发症，该装置在二尖瓣位置的使用已停止。
