Ishigooka M, Hayami S, Suzuki Y, Hashimoto T, Sasagawa I, Nakada T
Department of Urology, Yamagata University, Japan.
Eur Urol. 1996;29(1):85-9. doi: 10.1159/000473724.
To clarify the effect of aging on the histological composition of established benign prostatic hyperplasia (BPH), quantitative morphometric analyses were performed. Specimens were obtained from 23 patients who underwent transurethral resection of the prostate due to symptomatic BPH. Smooth muscle cells, fibrous tissue, glandular cells, glandular lumen and vascular tissue were quantified. Stromal and glandular components of established BPH did not correlate with age, whereas the proportion of vascular tissue was inversely correlated with age (r = -0.572, p = 0.0046). In the present series, the main characteristic of BPH tissue of elderly men appeared to be decreased vascularity.
为阐明衰老对已确诊的良性前列腺增生（BPH）组织学构成的影响，我们进行了定量形态学分析。样本取自23例因有症状的BPH而接受经尿道前列腺切除术的患者。对平滑肌细胞、纤维组织、腺细胞、腺腔和血管组织进行了定量分析。已确诊的BPH的基质和腺性成分与年龄无关，而血管组织的比例与年龄呈负相关（r = -0.572，p = 0.0046）。在本研究系列中，老年男性BPH组织的主要特征似乎是血管减少。
