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可乐定治疗不对称味觉性面部出汗：一项单病例试验

Clonidine in the management of asymmetrical gustatory facial sweating: an N-of-1 trial.

作者信息

Nesathurai S, Harvey D T

机构信息

Department of Rehabilitation Medicine, Boston University Medical Center Hospital, MA 02118-2393, USA.

出版信息

Arch Phys Med Rehabil. 1996 Sep;77(9):906-8. doi: 10.1016/s0003-9993(96)90280-4.

DOI:10.1016/s0003-9993(96)90280-4
PMID:8822684
Abstract

OBJECTIVE

To determine the efficacy of clonidine in the management of gustatory facial sweating (GFS) ipsilateral to an upper thoracic sympathectomy.

DESIGN

Placebo-controlled N-of-1 trial.

SETTING

Tertiary care referral center.

INTERVENTION

Clonidine patch that delivers 0.2mg/d.

OUTCOME MEASURE

Daily episodes of GFS are recorded. The severity of GFS is graded as mild, moderate, or severe, and a daily GFS score is calculated.

RESULTS

Clonidine was shown to significantly decrease (p < .05) the incidence and frequency of gustatory facial sweating.

摘要

目的

确定可乐定对上胸段交感神经切除术后同侧味觉性面部出汗（GFS）的治疗效果。

设计

安慰剂对照的单病例试验。

地点

三级医疗转诊中心。

干预措施

每日释放0.2毫克的可乐定贴片。

观察指标

记录GFS的每日发作次数。GFS的严重程度分为轻度、中度或重度，并计算每日GFS评分。

结果

可乐定可显著降低（p < 0.05）味觉性面部出汗的发生率和频率。

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Clonidine in the management of asymmetrical gustatory facial sweating: an N-of-1 trial.可乐定治疗不对称味觉性面部出汗：一项单病例试验
Arch Phys Med Rehabil. 1996 Sep;77(9):906-8. doi: 10.1016/s0003-9993(96)90280-4.
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