Chang C J, Achauer B M, Vander Kam V M
Department of Plastic and Reconstructive Surgery, Chang Gung Memorial Hospital, Linkou, Taiwan, ROC.
Changgeng Yi Xue Za Zhi. 1996 Jun;19(2):135-41.
A retrospective study of 73 patients treated for symptomatic hemangiomas of head and neck from May 1981 to April 1994 was conducted. Fifty-three females and 20 males ranging in age from 1 day of life to 11 years with the average age being 19 months were reviewed in the University of California, Irvine Medical Center. All patients were referred by pediatricians or family practitioners for evaluation and possible laser treatment. The lesions reported were particular troublesome because of obstruction of orifice(s), repeated ulceration, bleeding, subsequent pain or life threatening. Various lasers have been used for these patients including: CO2 laser [10], Argon laser/with intralesional steroid injection [33/14], Nd YAG laser [21], KTP laser [1] and Flashlamp-pumped pulsed dye laser (FPPDL)[8]. All treated lesions healed in 7 to 21 days (mean, 12 days). Complications associated with laser treatment, such as postoperative bleeding and infection were not seen. The symptoms were totally relieved from 7 days to 24 months (mean, 9 months). Combined with reconstructive surgery, the texture changes (7 patients) after laser treatment were corrected successfully. The outcome was graded by reduction in volume, improvement of color and texture of hemangioma as follow: Grade 1 - Poor (0-25%); Grade II - Fair (26-50%); Grade III - Good (51-75%); Grade IV - Excellent (76-100%). The final results of the patients are similar to what may be expected after spontaneous involution of a complicated hemangioma. In summary, complicated hemangiomas of head and neck in infancy have significant morbidity that can be efficiently avoided with the use of laser therapy.
对1981年5月至1994年4月期间接受治疗的73例头颈部有症状血管瘤患者进行了回顾性研究。加利福尼亚大学欧文医学中心对53名女性和20名男性进行了评估,这些患者年龄从1天至11岁不等,平均年龄为19个月。所有患者均由儿科医生或家庭医生转诊来进行评估及可能的激光治疗。所报告的病变特别麻烦,因为存在孔口阻塞、反复溃疡、出血、继发疼痛或危及生命的情况。已对这些患者使用了各种激光,包括:二氧化碳激光[10]、氩激光/联合病灶内注射类固醇[33/14]、钕钇铝石榴石激光[21]、磷酸钛氧钾激光[1]和闪光灯泵浦脉冲染料激光(FPPDL)[8]。所有接受治疗的病变在7至21天(平均12天)内愈合。未观察到与激光治疗相关的并发症,如术后出血和感染。症状在7天至24个月(平均9个月)内完全缓解。结合重建手术,成功纠正了激光治疗后出现的质地改变(7例患者)。根据血管瘤体积缩小、颜色和质地改善情况对结果进行分级如下:1级 - 差(0 - 25%);2级 - 尚可(26 - 50%);3级 - 良好(51 - 75%);4级 - 优秀(76 - 100%)。患者的最终结果与复杂血管瘤自然消退后预期的结果相似。总之,婴儿期头颈部复杂血管瘤具有显著的发病率,使用激光治疗可有效避免。