吸烟对气道动力学急性影响的检测：肺功能测试的关键与比较研究
Detection of acute effects of cigarette smoking on airway dynamics: A critical and comparative study of pulmonary function tests.
作者信息
Sobol B J, Van Voorhies L, Emirgil C
出版信息
Thorax. 1977 Jun;32(3):312-6. doi: 10.1136/thx.32.3.312.
Abstract
In an effort to determine which measure of airway dynamics was the most sensitive to airway obstruction, comparisons were made between a variety of tests. Twenty cigarette smokers were studied both before and immediately after smoking a cigarette. The maximum midexpiratory flow (FEV25-75) and the FEV1/FVC per cent were abnormal in the largest number of cases. Closing volume was abnormal in only one case. Significant worsening in function after smoking a cigarette occurred in airway resistance and specific conductance. A lesser degree of impairment in airway dynamics was evident from FEV25-75 and first-second expired volume. The closing volume showed no change.
摘要
为了确定哪种气道动力学指标对气道阻塞最敏感，对多种测试进行了比较。对20名吸烟者在吸烟前和吸烟后立即进行了研究。最大呼气中期流速（FEV25 - 75）和FEV1/FVC百分比在大多数病例中异常。闭合气量仅在1例中异常。吸烟后气道阻力和比传导率的功能显著恶化。从FEV25 - 75和第一秒与第二秒呼出量可明显看出气道动力学有较轻程度的损害。闭合气量无变化。
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