Oppenheimer S M, Kedem G, Martin W M
Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Clin Auton Res. 1996 Jun;6(3):131-40. doi: 10.1007/BF02281899.
The insular cortex is involved in cardiac regulation. The left insula is predominantly responsible for parasympathetic cardiovascular effects. Damage to this area could shift cardiovascular balance towards increased basal sympathetic tone (a pro-arrhythmic condition) and contribute to the excess cardiac mortality following stroke. Acute left insular stroke increased basal cardiac sympathetic tone and was associated with a decrease in randomness of heart rate variability. In addition, phase relationships between heart rate and blood pressure were disturbed, implying a disruption of oscillators involved in cardiovascular control. The insula appears to be involved in human heart rate regulation and damage to it may encourage a pro-arrhythmic state.
岛叶皮质参与心脏调节。左侧岛叶主要负责副交感神经对心血管的影响。该区域受损可能会使心血管平衡向基础交感神经张力增加（一种促心律失常状态）转变，并导致中风后心脏死亡率过高。急性左侧岛叶中风会增加基础心脏交感神经张力，并与心率变异性的随机性降低有关。此外，心率与血压之间的相位关系受到干扰，这意味着参与心血管控制的振荡器受到破坏。岛叶似乎参与人类心率调节，其损伤可能会促成促心律失常状态。
