Llanes F, Sanz-Ortega J, Suarez B, Sanz-Esponera J
Departamento Anatomia Patologica, Hospital Universitario San Carlos, Madrid, Spain.
J Periodontol. 1996 Jul;67(7):717-9. doi: 10.1902/jop.1996.67.7.717.
Oral metastases from hepatocellular carcinomas are rare. Case 1 was a 66-year-old male without previous history of liver disease who presented with metastasis to the gingival jaw mucosae on the lingual side. Case 2 was a 71-year-old male, with a previous history of diabetes, hepatitis, and cirrhosis who presented with metastasis to the right palatine tonsil. Oral metastases were the first manifestation of the hepatocellular carcinoma in both cases. A review of the literature disclosed 20 cases of hepatocellular carcinoma metastasizing to the oral cavity, 7 affecting the gingival mucosae and none of them affecting the palatine tonsil.
肝细胞癌的口腔转移罕见。病例1是一名66岁男性，既往无肝脏疾病史，出现舌侧牙龈颌黏膜转移。病例2是一名71岁男性，既往有糖尿病、肝炎和肝硬化病史，出现右侧腭扁桃体转移。在这两个病例中，口腔转移均为肝细胞癌的首发表现。文献回顾发现20例肝细胞癌转移至口腔，7例累及牙龈黏膜，无一例累及腭扁桃体。
