Ramón Ramirez José, Seoane Juan, Montero Juan, Esparza Gómez Germán C, Cerero Rocio
Pathology Service, "Gomez-Ulla" University Military Hospital, Madrid, Spain.
J Clin Periodontol. 2003 Oct;30(10):926-9. doi: 10.1034/j.1600-051x.2003.00391.x.
Oral metastatic tumours are uncommon and account for approximately 1% of malignant oral neoplasms.
If the cases where the oral location is in the jawbone, with secondary invasion to the oral soft tissue, are excluded, only 10 cases of gingival metastasis from hepatocellular carcinoma (HCC) have been previously reported in the literature. The clinicopathologic features of an HCC with gingival metastasis are reported. Six months after the multicentric HCC and alcoholic cirrhosis was diagnosed, a 65-year-old male patient presented a rapidly growing, lobulated and reddish exophytic lesion that was located in the gum in the incisal region of the upper jaw. The lesion was excised, and the final diagnosis of gingival metastasis of the HCC was established. Diagnostic investigations did not show any evidence of other metastatic lesions. This article describes a case with solitary metastasis from HCC in the gingiva, an event that, to our knowledge, has not been previously published.
The clinical appearance of isolated gingival metastasis from HCC in the present case mimicked a pyogenic granuloma.
口腔转移性肿瘤并不常见,约占口腔恶性肿瘤的1%。
如果排除口腔部位在颌骨且继发侵犯口腔软组织的病例,此前文献中仅报道过10例肝细胞癌(HCC)牙龈转移的病例。本文报道了1例发生牙龈转移的HCC的临床病理特征。在多中心HCC和酒精性肝硬化确诊6个月后,一名65岁男性患者上颌切牙区牙龈出现一个迅速生长、分叶状、红色的外生性病变。该病变被切除,最终确诊为HCC牙龈转移。诊断性检查未发现任何其他转移病变的证据。本文描述了1例HCC孤立性牙龈转移病例,据我们所知,此前尚未有过相关报道。
本病例中HCC孤立性牙龈转移的临床表现类似化脓性肉芽肿。