来自拟杆菌属接合转座子Tcr Emr 7853的红霉素抗性基因与球形芽孢杆菌的ermG几乎相同。
The erythromycin resistance gene from the Bacteroides conjugal transposon Tcr Emr 7853 is nearly identical to ermG from Bacillus sphaericus.
作者信息
Cooper A J, Shoemaker N B, Salyers A A
机构信息
Department of Microbiology, University of Illinois, Urbana 61801, USA.
出版信息
Antimicrob Agents Chemother. 1996 Feb;40(2):506-8. doi: 10.1128/AAC.40.2.506.
Abstract
Tcr Emr 7853, from Bacteroides thetaiotaomicron 7853, is a large chromosomal conjugative transposon which encodes resistance to both tetracycline (Tcr) and erythromycin (Emr). The erythromycin resistance gene of Tcr Emr 7853 did not cross-hybridize with ermF, the Emr gene found on previously studied Bacteroides regular and conjugative transposons. We have cloned and sequenced the erythromycin resistance gene from Tcr Emr 7853. The DNA sequence of this gene was 99.6% identical to that of ermG from Bacillus sphaericus.
摘要
来自嗜热栖热放线菌7853的Tcr Emr 7853是一种大型染色体接合转座子，它编码对四环素（Tcr）和红霉素（Emr）的抗性。Tcr Emr 7853的红霉素抗性基因与ermF没有交叉杂交，ermF是先前研究的普通拟杆菌和接合转座子上发现的Emr基因。我们已经从Tcr Emr 7853中克隆并测序了红霉素抗性基因。该基因的DNA序列与球形芽孢杆菌的ermG的DNA序列有99.6%的同一性。
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