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The erythromycin resistance gene from the Bacteroides conjugal transposon Tcr Emr 7853 is nearly identical to ermG from Bacillus sphaericus.来自拟杆菌属接合转座子Tcr Emr 7853的红霉素抗性基因与球形芽孢杆菌的ermG几乎相同。
Antimicrob Agents Chemother. 1996 Feb;40(2):506-8. doi: 10.1128/AAC.40.2.506.
2
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本文引用的文献

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Excision, transfer, and integration of NBU1, a mobilizable site-selective insertion element.可移动位点选择性插入元件NBU1的切除、转移与整合
J Bacteriol. 1993 Oct;175(20):6578-87. doi: 10.1128/jb.175.20.6578-6587.1993.
2
Cloning and sequence analysis of ermQ, the predominant macrolide-lincosamide-streptogramin B resistance gene in Clostridium perfringens.产气荚膜梭菌中主要的大环内酯-林可酰胺-链阳菌素B抗性基因ermQ的克隆与序列分析
Antimicrob Agents Chemother. 1994 May;38(5):1041-6. doi: 10.1128/AAC.38.5.1041.
3
Transfer of antibiotic resistance genes between gram-positive and gram-negative bacteria.革兰氏阳性菌与革兰氏阴性菌之间抗生素抗性基因的转移。
Antimicrob Agents Chemother. 1994 Jul;38(7):1447-51. doi: 10.1128/AAC.38.7.1447.
4
Insights into erythromycin action from studies of its activity as inducer of resistance.从红霉素作为耐药诱导剂的活性研究中获得的对其作用的见解。
Antimicrob Agents Chemother. 1995 Apr;39(4):797-805. doi: 10.1128/AAC.39.4.797.
5
Genetic analysis of clindamycin resistance in Bacteroides species.拟杆菌属中克林霉素耐药性的遗传分析。
J Infect Dis. 1983 Mar;147(3):551-8. doi: 10.1093/infdis/147.3.551.
6
Presence of two unique genes encoding macrolide-lincosamide-streptogramin resistance in members of the Bacteroides fragilis group as determined by DNA-DNA homology.通过DNA-DNA同源性测定，脆弱拟杆菌群成员中存在两个编码大环内酯-林可酰胺-链阳菌素抗性的独特基因。
J Antimicrob Chemother. 1984 Oct;14(4):329-38. doi: 10.1093/jac/14.4.329.
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Genetic organization of the broad-host-range IncP-1 plasmid R751.广宿主范围IncP-1质粒R751的基因组织。
J Bacteriol. 1980 Sep;143(3):1362-73. doi: 10.1128/jb.143.3.1362-1373.1980.
8
Regions in Bacteroides plasmids pBFTM10 and pB8-51 that allow Escherichia coli-Bacteroides shuttle vectors to be mobilized by IncP plasmids and by a conjugative Bacteroides tetracycline resistance element.拟杆菌属质粒pBFTM10和pB8 - 51中的区域，这些区域可使大肠杆菌 - 拟杆菌穿梭载体被IncP质粒和一个接合型拟杆菌四环素抗性元件所转移。
J Bacteriol. 1986 Jun;166(3):959-65. doi: 10.1128/jb.166.3.959-965.1986.
9
Cloning and analysis of ermG, a new macrolide-lincosamide-streptogramin B resistance element from Bacillus sphaericus.球形芽孢杆菌中一种新的大环内酯-林可酰胺-链阳霉素B抗性元件ermG的克隆与分析
J Bacteriol. 1987 Jan;169(1):340-50. doi: 10.1128/jb.169.1.340-350.1987.
10
Complete nucleotide sequence and transcription of ermF, a macrolide-lincosamide-streptogramin B resistance determinant from Bacteroides fragilis.脆弱拟杆菌中红霉素-林可酰胺-链阳菌素B耐药决定因子ermF的完整核苷酸序列及转录情况
J Bacteriol. 1986 Nov;168(2):523-33. doi: 10.1128/jb.168.2.523-533.1986.

来自拟杆菌属接合转座子Tcr Emr 7853的红霉素抗性基因与球形芽孢杆菌的ermG几乎相同。

The erythromycin resistance gene from the Bacteroides conjugal transposon Tcr Emr 7853 is nearly identical to ermG from Bacillus sphaericus.

作者信息

Cooper A J, Shoemaker N B, Salyers A A

机构信息

Department of Microbiology, University of Illinois, Urbana 61801, USA.

出版信息

Antimicrob Agents Chemother. 1996 Feb;40(2):506-8. doi: 10.1128/AAC.40.2.506.

DOI:10.1128/AAC.40.2.506
PMID:8834912
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC163148/
Abstract

Tcr Emr 7853, from Bacteroides thetaiotaomicron 7853, is a large chromosomal conjugative transposon which encodes resistance to both tetracycline (Tcr) and erythromycin (Emr). The erythromycin resistance gene of Tcr Emr 7853 did not cross-hybridize with ermF, the Emr gene found on previously studied Bacteroides regular and conjugative transposons. We have cloned and sequenced the erythromycin resistance gene from Tcr Emr 7853. The DNA sequence of this gene was 99.6% identical to that of ermG from Bacillus sphaericus.

摘要

来自嗜热栖热放线菌7853的Tcr Emr 7853是一种大型染色体接合转座子，它编码对四环素（Tcr）和红霉素（Emr）的抗性。Tcr Emr 7853的红霉素抗性基因与ermF没有交叉杂交，ermF是先前研究的普通拟杆菌和接合转座子上发现的Emr基因。我们已经从Tcr Emr 7853中克隆并测序了红霉素抗性基因。该基因的DNA序列与球形芽孢杆菌的ermG的DNA序列有99.6%的同一性。