Faka B, Api M, Fiçicioğlu C, Gürbüz A, Oral O
Acta Eur Fertil. 1994 Nov-Dec;25(6):351-3.
To determine whether the oral use of pentoxifylline improves the fertilization ability, concentration and motility of spermatozoa of poor fertilizer male subject.
Analysis of the spermiogram parameters before and after oral pentoxifylline administration.
Zeynep Kamil Women and Children's Hospital, Department of Infertility.
Fourteen healthy, untreated male partners of couples who applied to our infertility department and were found to have poor semen parameters.
Data of the semen analyses and fertilization rates are compared before and after treatment.
Before the treatment, the average percentage sperm motility and density were 30.1 +/- 8 (%) and 14.8 +/- 3.2 (10(6)/ml), respectively. The same parameters were found to be 37.8 +/- 13 (%) and 19.5 +/- 10 (10(6)/ml), respectively, following the treatment. Not significant, p = 0.08 and p = 0.116, respectively).
None of the semen parameters evaluated were improved by oral administration of pentoxifylline. Therefore pentoxifylline does not increase percentage motility and density of spermatozoa or the fertilization rates.
