Teff K L, Engelman K
Monell Chemical Senses Center, Philadelphia, PA 19104, USA.
Physiol Behav. 1996 Aug;60(2):567-73. doi: 10.1016/s0031-9384(96)80033-3.
The palatability of food has been shown to influence the cephalic phase reflexes. To determine if food palatability affects the magnitude of cephalic phase insulin release (CPIR) in humans, normal-weight women were asked to list foods that they found palatable and unpalatable. Subjects then stayed overnight in the hospital on two separate days. On each morning following an overnight fast, an intravenous line was inserted and arterialized venous blood drawn for the measurement of plasma insulin and glucose. Blood samples were taken prior to and following a modified sham-feed. Subjects sham-fed the palatable or unpalatable foods (that they had previously identified) for a 2-min period. Foods were administered in a counterbalanced order. During the protocol, hunger and food palatability were monitored. The Three Factor Eating Questionnaire was administered to assess eating attitudes. No significant difference in the magnitude of cephalic phase insulin release was found between the two treatments. However, a statistically significant correlation (r = 0.61, p < 0.05) was found between an individual's degree of dietary restraint as measured by the Three Factor Eating Questionnaire and the magnitude of CPIR. These data suggest that the sensory attributes of food may play less of a role in modulating CPIR than an individual's psychological attitude towards food.
食物的适口性已被证明会影响头期反射。为了确定食物适口性是否会影响人类头期胰岛素释放（CPIR）的幅度，研究人员让体重正常的女性列出她们认为可口和不可口的食物。然后，受试者在医院分别住两个晚上。在每个禁食过夜后的早晨，插入静脉输液管并采集动脉化静脉血，以测量血浆胰岛素和葡萄糖。在改良假饲前后采集血样。受试者对可口或不可口的食物（她们之前已确定）进行2分钟的假饲。食物以平衡的顺序给予。在实验过程中，监测饥饿感和食物适口性。使用三因素饮食问卷来评估饮食态度。两种处理之间在头期胰岛素释放幅度上未发现显著差异。然而，通过三因素饮食问卷测量的个体饮食限制程度与CPIR幅度之间存在统计学上的显著相关性（r = 0.61，p < 0.05）。这些数据表明，与个体对食物的心理态度相比，食物的感官属性在调节CPIR方面可能起的作用较小。
