Eur J Obstet Gynecol Reprod Biol. 1996 Aug;67(2):121-6. doi: 10.1016/0301-2115(96)02448-7.
Forty-nine obstetricians from three European countries were asked when they would advise delivery for a preterm fetus failing to thrive in utero, given various gestational ages, and a range of either umbilical artery Doppler flow velocity waveforms or CTG variability measures. Their responses indicated a wide area of disagreement about the correct timing of delivery, and a willingness to randomize patients to clinical trials of management. The area of uncertainty corresponded to the gestational age and Doppler bands at which participants have been entered to the pilot phase of a randomised trial of timed delivery, the Growth Restriction Intervention Trial (GRIT).
来自三个欧洲国家的49位产科医生被问及,对于不同孕周且伴有一系列脐动脉多普勒血流速度波形或CTG变异指标的宫内生长受限早产胎儿,他们会建议何时进行分娩。他们的回答表明,在正确的分娩时机上存在广泛的分歧,并且愿意将患者随机分配到管理的临床试验中。不确定性区域与参与者已进入定时分娩随机试验(生长受限干预试验,GRIT)试点阶段的孕周和多普勒波段相对应。