Fedorov V I, Perov Iu L
Biull Eksp Biol Med. 1977 Jun;83(6):656-9.
The aorta was partially constricted between the origins of the two renal arteries in rats. The renin activity was studied separately in the capillary parts of the isolated glomeruli and in their arterioles. The renin activity was found in the capillary parts of the glomeruli 3 to 4 weeks after the constriction. The rough and smooth endoplasmic reticulum and the Golgi complex of the mesangial cells were activated at this period. The authors consider these results as a confirmation of the hypothesis on the reserve renin production by mesangial cells under prolonged decrease of renal circulation.
在大鼠的两条肾动脉起始部之间对主动脉进行部分缩窄。分别对分离肾小球的毛细血管部分及其小动脉中的肾素活性进行研究。缩窄后3至4周，在肾小球的毛细血管部分发现了肾素活性。在此期间，系膜细胞的粗面内质网、滑面内质网和高尔基体被激活。作者认为这些结果证实了关于在肾循环长期减少的情况下系膜细胞产生储备肾素的假说。
