Roehrs T, Salin-Pascual R, Merlotti L, Rosenthal L, Roth T
Henry Ford Hospital, Sleep Disorders and Research Center, Detroit, Michigan 48202, USA.
Sleep. 1996 Jun;19(5):417-22. doi: 10.1093/sleep/19.5.417.
Phase advanced sleep (by 4 hours) was studied in 28 healthy, normal men and women, aged 21-50 years, without nocturnal sleep or daytime sleepiness complaints. Eleven subjects (6 men and 5 women) with moderately short (< or = 10 minutes) average daily sleep latencies on the multiple sleep latency test (MSLT) were compared to 17 (11 men and 6 women) with relatively long (> or = 12 minutes) latencies. Nocturnal sleep on both a baseline and a shift night differed between the groups. The moderately "sleepy" group had shorter sleep latencies and less wakefulness during sleep than the moderately "alert" group. The phase advanced sleep schedule reduced sleep efficiency in both groups, but the moderately sleepy group showed a lessened effect of the shift. Additionally, sleep efficiency was reduced in the moderately sleepy group only during the first 2 hours of the sleep period, while sleep efficiency was uniformly disturbed in the moderately alert group throughout the night during the phase advance.
对28名年龄在21至50岁之间、无夜间睡眠或日间嗜睡主诉的健康正常男女进行了提前4小时的睡眠阶段研究。在多次睡眠潜伏期试验（MSLT）中，将11名平均每日睡眠潜伏期适度较短（≤10分钟）的受试者（6名男性和5名女性）与17名（11名男性和6名女性）潜伏期相对较长（≥12分钟）的受试者进行了比较。两组在基线期和轮班期的夜间睡眠情况有所不同。与适度“警觉”组相比，适度“嗜睡”组的睡眠潜伏期更短，睡眠期间的觉醒时间更少。提前睡眠时间表降低了两组的睡眠效率，但适度嗜睡组的轮班影响较小。此外，仅在睡眠期的前两小时，适度嗜睡组的睡眠效率降低，而在提前睡眠阶段，适度警觉组的睡眠效率在整个夜间均受到均匀干扰。
