Matsunaga A T, Shafer F E
Department of Hematology-Oncology, Children's Hospital Oakland, CA 94609, USA.
J Pediatr Hematol Oncol. 1996 May;18(2):223-6. doi: 10.1097/00043426-199605000-00028.
An acquired inhibitor to factor X is an uncommon clinical finding in the pediatric population. We report the development of this type of inhibitor in a pediatric patient with extensive burns.
The patient's clinical course was complicated by persistent blood loss from the burn site.
Characterization of the inhibitor demonstrated that it bound to the light chain of factor X.
The inhibitor disappeared after treatment with i.v. immunoglobulin.
获得性X因子抑制剂在儿科人群中是一种不常见的临床发现。我们报告了一名大面积烧伤的儿科患者出现这种类型抑制剂的情况。
患者的临床病程因烧伤部位持续失血而复杂化。
对该抑制剂的特性分析表明，它与X因子的轻链结合。
静脉注射免疫球蛋白治疗后，该抑制剂消失。
