Kaissling B, Peter S, Kriz W
Cell Tissue Res. 1977 Jul 26;182(1):111-8. doi: 10.1007/BF00222059.
Examination of serial semithin sections of rat kidney cortex and a subsequent electron microscopic study of selected areas revealed that the characteristic epithelium of the cortical part of the thick ascending limb of Henle extends for a varying distance beyond the macula densa. The transition from the relatively thin epithelium of the thick ascending limb at this site to the three--or even four--fold thicker epithelium of the convoluted part of the distal tubule is sharply defined and occurs without the interposition of an intermediate cell type. The position of the macula densa at the end but still clearly within the ascending limb of Henle's loop is functionally interpreted to guarantee the separation of the sensor point macula densa from disturbing influences which might arise from the secretory activity of the subsequent tubular portion.
对大鼠肾皮质连续半薄切片的检查以及随后对选定区域的电子显微镜研究表明，亨氏袢厚升支皮质部的特征性上皮细胞在致密斑后方延伸不同距离。在此部位，厚升支相对较薄的上皮细胞向远曲小管盘曲部三倍甚至四倍厚的上皮细胞的转变界限清晰，且不存在中间细胞类型的过渡。致密斑位于亨氏袢升支末端但仍明显在其内部，从功能上解释，这可确保传感点致密斑免受后续肾小管部分分泌活动可能产生的干扰影响。
