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腰椎间盘突出症手术后的脊椎椎间盘炎

[Spondylodiscitis after operation for lumbar disc herniation].

作者信息

Imae S, Igarashi S, Koyama T

机构信息

Department of Neurosurgery, Ohtsu Municipal Hospital, Shiga, Japan.

出版信息

No Shinkei Geka. 1996 Feb;24(2):149-55.

PMID:8849475
Abstract

Postoperative spondylodiscitis (POD) is a rare but severe complication of lumbar disc surgery. There were five patients with POD among 875 patients undergoing surgery for herniated lumbar discs, in the last 16 years. For detecting risk factor of discitis, a POD group of 5 patients was matched to a control group of 870 patients with respect to sex, age, disc type and operation. In five patients with POD follow-up evaluation of clinical symptoms, laboratory data were obtained, and magnetic resonance (MR) imaging was performed. A significant difference between the POD group and the control group was confirmed in sex, operation time and the volume of bleeding during operation. However, there was no significant difference confirmed due to age, disc type, disc level and operative procedure. In the case of males or prolonged operation time or increase of the volume of bleeding, POD may be more frequently observed. All five patients had a period of pain relief after their operations and then reported increasing low back pain with no focal signs. At diagnosis of POD all patients had an erythrocyte sedimentation rate (ESR) greater than 30 per hour and C-reactive protein (CRP) higher than 2.5. After treatment by antibiotics, low back pain gradually receded along with decrease of ESR and CRP. About 40 days later, these patients were almost free of back pain and ESR and CRP were within normal range. MRT1-weighted image during the acute phase demonstrated remarkably decreased signal intensity with loss of distinction between vertebral body and disc space. T2-weighted image showed increased signal intensity in the adjacent vertebral bodies and end-plates. Gadolinium-enhanced T1-weighted image had homogenous enhancement of vertebral body and disc space. During the subacute phase, however, T1-weighted image demonstrated moderately decreased signal intensity noted in the posteroinferior portion of the L5 vertebral body and the narrowed L5/S1 disc space. T2-weighted image showed iso signal intensity in L5 and S1 vertebral bodies. Gadolinium-enhanced T1-weighted image had mild homogenous enhancement in the posteroinferior portion of the L5 vertebral body. Three months after treatment of POD, there was major signal change in neither T1 nor T2 weighted images, though T2 showed subtle abnormalities with decreased signal intensity adjacent to the L5/S1 disc space.

摘要

术后脊椎椎间盘炎(POD)是腰椎间盘手术中一种罕见但严重的并发症。在过去16年中,875例行腰椎间盘突出症手术的患者中有5例发生了POD。为了检测椎间盘炎的危险因素,将5例POD患者组成的POD组与870例患者组成的对照组在性别、年龄、椎间盘类型和手术方面进行匹配。对5例POD患者进行临床症状的随访评估,获取实验室数据,并进行磁共振(MR)成像检查。POD组与对照组在性别、手术时间和术中出血量方面存在显著差异。然而,在年龄、椎间盘类型、椎间盘节段和手术方式方面未发现显著差异。男性、手术时间延长或出血量增加时,POD的发生率可能更高。所有5例患者术后均有一段时间的疼痛缓解,随后均出现下腰痛加重且无局部体征。诊断POD时,所有患者的红细胞沉降率(ESR)均大于30/小时,C反应蛋白(CRP)均高于2.5。经抗生素治疗后,下腰痛随ESR和CRP的降低而逐渐减轻。约40天后,这些患者几乎无腰痛,ESR和CRP均在正常范围内。急性期磁共振T1加权像显示信号强度明显降低,椎体与椎间盘间隙分界不清。T2加权像显示相邻椎体和终板信号强度增加。钆增强T1加权像显示椎体和椎间盘间隙均匀强化。然而,在亚急性期,T1加权像显示L5椎体后下部信号强度中度降低,L5/S1椎间盘间隙变窄。T2加权像显示L5和S1椎体等信号强度。钆增强T1加权像显示L5椎体后下部轻度均匀强化。POD治疗3个月后,T1加权像和T2加权像均未出现明显信号改变,不过T2像显示L5/S1椎间盘间隙相邻处信号强度降低,有轻微异常。

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