Anneroth G, Sigurdson A
Acta Odontol Scand. 1983;41(2):75-86. doi: 10.3109/00016358309162306.
175 'epulides' were studied clinically and histologically. The lesions were histologically reclassified into three groups: granulomatous, fibromatous and giant cell lesions. The granulomatous group was four times and the giant cell group 1.5 times more frequent in females. It is suggested that the expression epulis should be abandoned as a microscopic designation for lesions in the oral mucosa, as it is only a non-specific topographico-clinical concept comprising histogenetically and histomorphologically differing lesions and therefore does not represent a uniform group. The suggested new terms for the three types of hyperplastic lesions are oral mucosal granulomatous hyperplasias (including such diagnostic terms as granulomatous gingivitis, gingivitis of pregnancy, granuloma gravidarium, pyogenic granuloma, epulis angiomatosa and epulis telangiectaticum), oral mucosal fibrous hyperplasias (including such diagnostic terms as fibrous epulis, epulis fissuratum, fibroepithelial lesions, denture injury tumor and peripheral odontogenic fibroma) and oral mucosal giant cell hyperplasia (including such diagnostic terms as peripheral giant cell granuloma and giant cell epulis).
对175例“龈瘤”进行了临床和组织学研究。这些病变在组织学上被重新分类为三组：肉芽肿性、纤维瘤性和巨细胞性病变。肉芽肿性病变组在女性中的发生率是男性的四倍，巨细胞性病变组在女性中的发生率是男性的1.5倍。有人建议，“龈瘤”这一表述应不再用作口腔黏膜病变的微观命名，因为它只是一个非特异性的地形学 - 临床概念，包含组织发生学和组织形态学上不同的病变，因此并不代表一个统一的类别。对于这三种增生性病变建议使用的新术语是口腔黏膜肉芽肿性增生（包括肉芽肿性牙龈炎、妊娠性牙龈炎、妊娠性肉芽肿、化脓性肉芽肿、血管瘤性龈瘤和毛细血管扩张性龈瘤等诊断术语）、口腔黏膜纤维性增生（包括纤维性龈瘤、裂隙性龈瘤、纤维上皮性病变、义齿损伤性瘤和外周性牙源性纤维瘤等诊断术语）和口腔黏膜巨细胞增生（包括外周性巨细胞肉芽肿和巨细胞龈瘤等诊断术语）。
