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心脏过敏反应中血栓素释放的放射免疫测定

Radioimmunological determination of thromboxane release in cardiac anaphylaxis.

作者信息

Anhut H, Bernauer W, Peskar B A

出版信息

Eur J Pharmacol. 1977 Jul 1;44(1):85-8. doi: 10.1016/0014-2999(77)90120-0.

DOI:10.1016/0014-2999(77)90120-0
PMID:885162
Abstract

A sensitive and specific radioimmunoassay for thromboxane B2 were detected in perfusates of anaphylactic guinea pig hearts. Indomethacin decreased thromboxane B2 levels in the perfusates to below the detection limit of the radioimmunoassay and concomitantly delayed the onset of coronary vasoconstriction after antigenic challenge.

摘要

在过敏性豚鼠心脏灌流液中检测到一种灵敏且特异的血栓素B2放射免疫分析法。吲哚美辛可使灌流液中血栓素B2水平降至放射免疫分析法的检测限以下,并同时延迟抗原攻击后冠状动脉收缩的起始时间。

相似文献

1
Radioimmunological determination of thromboxane release in cardiac anaphylaxis.心脏过敏反应中血栓素释放的放射免疫测定
Eur J Pharmacol. 1977 Jul 1;44(1):85-8. doi: 10.1016/0014-2999(77)90120-0.
2
Effects of exogenous prostaglandins on the release of leukotriene C4-like immunoreactivity and on coronary flow in indomethacin-treated anaphylactic guinea-pig hearts.外源性前列腺素对消炎痛处理的过敏豚鼠心脏中白三烯C4样免疫反应性释放及冠脉血流的影响。
Naunyn Schmiedebergs Arch Pharmacol. 1984 Jul;326(4):368-74. doi: 10.1007/BF00501445.
3
Effect of exogenous 5,8,11,14,17-eicosapentaenoic acid on cardiac anaphylaxis.外源性5,8,11,14,17-二十碳五烯酸对心脏过敏反应的影响。
Br J Pharmacol. 1987 Feb;90(2):315-25. doi: 10.1111/j.1476-5381.1987.tb08961.x.
4
Pharmacological modification of thromboxane and prostaglandin release in cardiac anaphylaxis.心脏过敏反应中血栓素和前列腺素释放的药理学调节
Prostaglandins. 1978 May;15(5):889-900. doi: 10.1016/0090-6980(78)90156-9.
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Prostaglandin, slow-reacting substance, and histamine release from anaphylactic guinea-pig hearts, and its pharmacological modification.前列腺素、慢反应物质及组胺从过敏豚鼠心脏中的释放及其药理学修饰。
Naunyn Schmiedebergs Arch Pharmacol. 1975;289(1):65-76. doi: 10.1007/BF00498030.
6
Thromboxane and prostacyclin release during cardiac immediate hypersensitivity reactions in vitro.体外心脏速发型超敏反应期间血栓素和前列环素的释放
J Pharmacol Exp Ther. 1981 Apr;217(1):157-61.
7
Pharmacological modification of leukotriene release and coronary constrictor effect in cardiac anaphylaxis.心脏过敏反应中白三烯释放及冠状动脉收缩效应的药理学调节
Adv Prostaglandin Thromboxane Leukot Res. 1985;13:47-50.
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Involvement of endoperoxides and thromboxanes in anaphylactic reactions.内过氧化物和血栓素在过敏反应中的作用。
Adv Prostaglandin Thromboxane Res. 1976;1:495-501.
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Prostaglandins and cardiac anaphylaxis.前列腺素与心脏过敏反应
Life Sci. 1976 Jun 1;18(11):1255-64. doi: 10.1016/0024-3205(76)90202-2.
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Effect of inhibition of synthesis and receptor antagonism of SRS-A in cardiac anaphylaxis.SRS-A合成抑制及受体拮抗在心脏过敏反应中的作用
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Dig Dis Sci. 1993 Aug;38(8):1441-9. doi: 10.1007/BF01308601.
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Effect of exogenous and endogenous prostacyclin on the contractility of rabbit splenic capsular smooth muscle.外源性和内源性前列环素对兔脾包膜平滑肌收缩性的影响。
Naunyn Schmiedebergs Arch Pharmacol. 1980 Jul;312(3):245-53. doi: 10.1007/BF00499154.
3
The actions of leukotrienes C4 and D4 on guinea-pig isolated hearts.白三烯C4和D4对豚鼠离体心脏的作用。
Br J Pharmacol. 1982 May;76(1):169-76. doi: 10.1111/j.1476-5381.1982.tb09203.x.
4
Effects of leukotrienes C4 and D4 on guinea-pig heart and the participation of SRS-A in the manifestations of guinea-pig cardiac anaphylaxis.白三烯C4和D4对豚鼠心脏的作用以及慢反应物质A在豚鼠心脏过敏反应表现中的参与情况。
Agents Actions. 1983 Apr;13(2-3):182-7. doi: 10.1007/BF01967327.
5
Coronary vasoconstrictor and vasodilator actions of arachidonic acid in the isolated perfused heart of the rat.花生四烯酸在大鼠离体灌流心脏中的冠状动脉收缩和舒张作用。
Br J Pharmacol. 1982 Feb;75(2):269-86. doi: 10.1111/j.1476-5381.1982.tb08783.x.
6
Effect of inhibition of synthesis and receptor antagonism of SRS-A in cardiac anaphylaxis.SRS-A合成抑制及受体拮抗在心脏过敏反应中的作用
Br J Pharmacol. 1983 Sep;80(1):73-80. doi: 10.1111/j.1476-5381.1983.tb11051.x.
7
Effect of histamine, acetylcholine and compound 48/80 on bronchoconstriction and release of eicosanoids in the dog.组胺、乙酰胆碱和化合物48/80对犬支气管收缩和类花生酸释放的影响。
Agents Actions. 1984 Oct;15(3-4):153-61. doi: 10.1007/BF01972342.
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The importance of endogenous prostaglandins other than prostacyclin, for the modulation of contractility of some rabbit blood vessels.除前列环素外的内源性前列腺素对某些兔血管收缩性调节的重要性。
Br J Pharmacol. 1984 Apr;81(4):623-30. doi: 10.1111/j.1476-5381.1984.tb16127.x.
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Effects of exogenous prostaglandins on the release of leukotriene C4-like immunoreactivity and on coronary flow in indomethacin-treated anaphylactic guinea-pig hearts.外源性前列腺素对消炎痛处理的过敏豚鼠心脏中白三烯C4样免疫反应性释放及冠脉血流的影响。
Naunyn Schmiedebergs Arch Pharmacol. 1984 Jul;326(4):368-74. doi: 10.1007/BF00501445.
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Naunyn Schmiedebergs Arch Pharmacol. 1981 Feb;316(1):1-7. doi: 10.1007/BF00507219.