Imamura S, Ohnishi A, Yamamoto T, Nagaki J, Ikeda M
Department of Neurology, University of Occupational and Environmental Health, Japan.
J UOEH. 1996 Mar 1;18(1):1-5. doi: 10.7888/juoeh.18.1.
The evaluation of the density of the active sweat gland on the dorsum of the foot induced by iontophoresis of 1% pilocarpine was made repeatedly using the silastic impression mold technique in 83 subjects (52 normal volunteers: 24 subjects younger than 50 years of age and 28 subjects 50 years of age or older, 20 men and 32 women: 20 diabetic patients and 11 patients with other neurological disorders), from 12 to 82 years of age, and the reliability of such evaluation was assessed. After 8 to 14 days following the first evaluation, the second one was performed. The reliability was expressed as an intra-class correlation. The intra-class correlation was greater in the subjects 50 years of age or older (0.909) than in the subjects younger than 50 years of age (0.653). It was similar between males (0.921) and females (0.803). On the other hand, it was less in diabetic patients (0.543) than in the normal volunteers (0.857) and patients with other neurological disorders (0.809). The silastic impression mold technique is widely applicable in evaluating the sweat gland function. However, it should be kept in mind that the reliability is variable among the groups defined clinically and that it is low in the diabetic patients.
采用硅橡胶印模技术，对83名受试者（52名正常志愿者：24名年龄小于50岁，28名年龄50岁及以上，20名男性和32名女性；20名糖尿病患者和11名患有其他神经系统疾病的患者），年龄在12至82岁之间，反复进行1%毛果芸香碱离子导入诱发的足部背侧活跃汗腺密度评估，并评估该评估的可靠性。在首次评估后的8至14天进行第二次评估。可靠性用组内相关系数表示。50岁及以上受试者的组内相关系数（0.909）高于50岁以下受试者（0.653）。男性（0.921）和女性（0.803）之间相似。另一方面，糖尿病患者的组内相关系数（0.543）低于正常志愿者（0.857）和患有其他神经系统疾病的患者（0.809）。硅橡胶印模技术广泛适用于评估汗腺功能。然而，应记住，在临床定义的各组之间可靠性存在差异，且在糖尿病患者中可靠性较低。
