Nakagome Y, Kitagawa T, Iinuma K, Matsunaga E, Shinoda T
Hum Genet. 1977 Jul 26;37(3):255-60. doi: 10.1007/BF00393606.
A huge 'satellite' (22s+) was observed in a mentally retarded and malformed girl. It consisted of constitutive heterochromatin based on the C-band technique (CBG). In neither of the parents was the variant observed. Genetic marker studies revealed that the father was, indeed, the father of the proposita (probability, 99.8%). It is emphasized that caution must be taken in the use of chromosome variants for paternity dispute cases.
在一名智力发育迟缓且有畸形的女孩身上观察到一个巨大的“卫星”（22s+）。基于C带技术（CBG），它由组成型异染色质构成。在父母双方中均未观察到这种变异。基因标记研究表明，父亲确实是先证者的父亲（概率为99.8%）。需要强调的是，在亲子鉴定案件中使用染色体变异时必须谨慎。
