Sun N C, Sun C R, Chu E H
Hum Genet. 1977 Jul 26;37(3):279-84. doi: 10.1007/BF00393609.
In the progeny of somatic cell hybrids formed by fusion of human lymphocytes and Chinese hamster mutant cells, a single human chromosome A2 was selectively retained when grown in appropriate medium. Spontaneous breakage of this chromosome in different hybrid subclones led to the assignment of the gene for galactose-1-phosphate uridyltransferase to the centromeric region of this chromosome (2q11 leads to 2q14). This gene is shown to be syntenic to the previously mapped genes for acid phosphatase 1 and malate dehydrogenase 1.
在由人淋巴细胞与中国仓鼠突变细胞融合形成的体细胞杂种后代中，当在合适的培养基中培养时，单条人类染色体A2被选择性保留。这条染色体在不同杂种亚克隆中的自发断裂导致将1-磷酸半乳糖尿苷转移酶基因定位到该染色体的着丝粒区域（2q11至2q14）。该基因被证明与先前定位的酸性磷酸酶1和苹果酸脱氢酶1基因同线。
