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慢性疲劳综合征

Chronic fatigue syndrome.

作者信息

Sharpe M

机构信息

Department of Psychiatry, University of Oxford, United Kingdom.

出版信息

Psychiatr Clin North Am. 1996 Sep;19(3):549-73. doi: 10.1016/s0193-953x(05)70305-1.

DOI:10.1016/s0193-953x(05)70305-1
PMID:8856816
Abstract

Chronic fatigue syndrome (CFS) is a medically unexplained illness characterized by chronic, disabling fatigue, impaired concentration, muscle pain, and other somatic symptoms. The conceptual difficulties associated with all medically unexplained illnesses contribute to the controversy surrounding CFS, which has centered around whether it is best regarded as a medical or as a psychiatric condition. Clinically, such an approach is not helpful, and current research suggests that both pathophysiologic changes and psychosocial factors are important. Pragmatic management based on a detailed assessment of the individual is outlined.

摘要

慢性疲劳综合征(CFS)是一种医学上无法解释的疾病,其特征为慢性、使人衰弱的疲劳、注意力不集中、肌肉疼痛及其他躯体症状。与所有医学上无法解释的疾病相关的概念难题导致了围绕慢性疲劳综合征的争议,该争议主要集中在它最好被视为一种医学病症还是精神病症。在临床上,这种方法并无帮助,而目前的研究表明病理生理变化和心理社会因素都很重要。文中概述了基于对个体进行详细评估的务实管理方法。

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Evidence for T-helper 2 shift and association with illness parameters in chronic fatigue syndrome (CFS).慢性疲劳综合征(CFS)中辅助性T细胞2偏移及其与疾病参数相关性的证据。
Bull IACFS ME. 2008 Fall;16(3):19-33.
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The associations between basal salivary cortisol and illness symptomatology in chronic fatigue syndrome.慢性疲劳综合征中基础唾液皮质醇与疾病症状学之间的关联。
J Appl Biobehav Res. 2008 Jan 1;13:157-180. doi: 10.1111/j.1751-9861.2008.00033.x.
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Gene expression in peripheral blood leukocytes in monozygotic twins discordant for chronic fatigue: no evidence of a biomarker.
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PLoS One. 2009 Jun 5;4(6):e5805. doi: 10.1371/journal.pone.0005805.
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The prevalence of self-reported chronic fatigue in a U.S. twin registry.美国双胞胎登记处中自我报告的慢性疲劳患病率。
J Psychosom Res. 2005 Nov;59(5):283-90. doi: 10.1016/j.jpsychores.2005.05.008.
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