Nakagawa T, Aiba T, Shiotani H, Tomiyama K, Nakai Y
Department of Otorhinolaryngology, Yodogawa Christian Hospital, Osaka, Japan.
Eur Arch Otorhinolaryngol. 1996;253(6):371-3. doi: 10.1007/BF00178295.
Among nerve cells of vertebrates, the olfactory epithelia are uncommon in their capacity for cell turnover. Apoptosis is well known to play a key role in maintaining homeostasis in continuously renewing tissues. We examined whether true apoptosis occurred in the normal olfactory epithelia of healthy adult guinea pigs using nucleic acid labeling. Subsequently, apoptosis was recognized in olfactory nerve cells, indicating that apoptosis might play a role in turnover of the olfactory epithelium.
在脊椎动物的神经细胞中，嗅觉上皮细胞在细胞更新能力方面并不常见。众所周知，细胞凋亡在维持持续更新组织的内环境稳定中起关键作用。我们使用核酸标记检查了健康成年豚鼠正常嗅觉上皮中是否发生了真正的细胞凋亡。随后，在嗅神经细胞中识别出细胞凋亡，这表明细胞凋亡可能在嗅觉上皮的更新中起作用。
