Schwartz J, Gonzalez J, Rosenberg R, Fujihara K, Cottrill C M, Klainer A S, Bisaccia E
Department of Internal Medicine, Morristown Memorial Hospital, NJ 07960-1956, USA.
South Med J. 1996 Oct;89(10):999-1000. doi: 10.1097/00007611-199610000-00014.
The clinical spectrum of retroviruses is expanding rapidly. Human T-cell lymphotropic virus type I (HTLV-I) was the first retrovirus to be described, and its role had been established in adult T-cell leukemia/lymphoma and tropical spastic paraparesis. We report the case of a 35-year-old woman with HTLV-I and the unusual combination of cutaneous T-cell lymphoma, tropical spastic paraparesis, cerebral vasculitis, and protein S deficiency. We discuss the relationship of all her diseases to HTLV-I.
逆转录病毒的临床谱正在迅速扩展。人类嗜T淋巴细胞病毒I型(HTLV-I)是首个被描述的逆转录病毒,其在成人T细胞白血病/淋巴瘤和热带痉挛性截瘫中的作用已得到确立。我们报告了一例35岁患有HTLV-I的女性病例,其患有皮肤T细胞淋巴瘤、热带痉挛性截瘫、脑血管炎和蛋白S缺乏症等罕见的疾病组合。我们讨论了她所有疾病与HTLV-I的关系。