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希腊一家转诊医院对棘球蚴性心脏病的15年监测。

Fifteen year surveillance of echinococcal heart disease from a referral hospital in Greece.

作者信息

Kardaras F, Kardara D, Tselikos D, Tsoukas A, Exadactylos N, Anagnostopoulou M, Lolas C, Anthopoulos L

机构信息

Department of Cardiology, Evangelismos General Hospital, Athens, Greece.

出版信息

Eur Heart J. 1996 Aug;17(8):1265-70. doi: 10.1093/oxfordjournals.eurheartj.a015045.

Abstract

Ten cases of hydatid heart disease were treated over a 15-year period (1980-1995). Cysts were located in the left ventricular wall (four patients), right ventricular wall (one patient), interventricular septum (one patient), interatrial septum (one patient), right atrium (one patient), pericardial cavity (one patient) and in multiple loci (one patient). Apart from two asymptomatic cases, clinical manifestations included chest pain (four patients), anaphylactic shock (one patient), constrictive pericarditis (one patient), congestive heart failure (one patient) and arterial embolism (one patient). Computed tomography was found useful in the detection of hydatid cysts and also in the determination of their morphology. Magnetic resonance was performed in three patients, with satisfactory imaging. Three out of the 10 patients died: rupture of pulmonary echinococcal cyst (one patient), massive pulmonary hydatid embolism (one patient) and rupture of an undiagnosed hydatid cyst of the right atrium during cannulation for cardiopulmonary bypass (one patient). One other patient experienced recurrent systemic embolism and became hemiplegic. Six patients were successfully treated. In five patients, the cysts were excised by open heart surgery, while in one by pericardiectomy. In addition, antiparasitic drugs were successfully used in two patients with long-term satisfactory results. In conclusion, cardiac echinococcosis is associated with an increased risk of potentially lethal complications. Newer techniques of cardiac imaging have helped locate the cysts while surgical removal may offer cure. Some patients responded to specific long-term drug treatment.

摘要

在15年期间(1980 - 1995年)共治疗了10例包虫性心脏病患者。囊肿位于左心室壁(4例患者)、右心室壁(1例患者)、室间隔(1例患者)、房间隔(1例患者)、右心房(1例患者)、心包腔(1例患者)以及多个部位(1例患者)。除2例无症状病例外,临床表现包括胸痛(4例患者)、过敏性休克(1例患者)、缩窄性心包炎(1例患者)、充血性心力衰竭(1例患者)和动脉栓塞(1例患者)。计算机断层扫描被发现有助于检测包虫囊肿及其形态的确定。3例患者进行了磁共振成像,成像效果令人满意。10例患者中有3例死亡:肺棘球蚴囊肿破裂(1例患者)、大量肺包虫栓塞(1例患者)以及在体外循环插管期间右心房未被诊断出的包虫囊肿破裂(1例患者)。另1例患者发生反复全身性栓塞并偏瘫。6例患者得到成功治疗。5例患者通过心脏直视手术切除囊肿,1例通过心包切除术切除。此外,抗寄生虫药物成功用于2例患者,长期效果良好。总之,心脏包虫病伴有潜在致命并发症风险增加。心脏成像的新技术有助于定位囊肿,而手术切除可能治愈疾病。一些患者对特定的长期药物治疗有反应。

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