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正常儿童与脊柱侧弯儿童的血浆生长调节素活性

Plasma somatomedin activity in normal and scoliotic children.

作者信息

Spencer G S, Zorab P A

出版信息

Pediatr Res. 1977 Aug;11(8):883-5. doi: 10.1203/00006450-197708000-00005.

DOI:10.1203/00006450-197708000-00005
PMID:887307
Abstract

In a study of plasma somatomedin activity in childhood scoliosis a group of five patients with congenital scoliosis was found to have significantly lower plasma somatomedin levels compared with a group of 20 normal children. A group of 52 patients with "idiopathic" scoliosis had normal plasma somatomedin levels. There is no apparent difference in the plasma somatomedin activity between the sexes, and no change in plasma somatomedin activity with chronologic age in these children, suggesting that normal adult somatomedin levels have been reached.

摘要

在一项关于儿童脊柱侧弯患者血浆生长调节素活性的研究中,发现一组5例先天性脊柱侧弯患者的血浆生长调节素水平明显低于20例正常儿童。一组52例“特发性”脊柱侧弯患者的血浆生长调节素水平正常。这些儿童中,血浆生长调节素活性在性别之间无明显差异,且不随年龄增长而变化,这表明已达到正常成人的生长调节素水平。

相似文献

1
Plasma somatomedin activity in normal and scoliotic children.正常儿童与脊柱侧弯儿童的血浆生长调节素活性
Pediatr Res. 1977 Aug;11(8):883-5. doi: 10.1203/00006450-197708000-00005.
2
Growth hormone and somatomedin A in girls with adolescent idiopathic scoliosis.青少年特发性脊柱侧凸女孩中的生长激素和生长调节素A
Acta Paediatr Scand. 1976 Sep;65(5):547-52. doi: 10.1111/j.1651-2227.1976.tb04930.x.
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[Activity of blood somatomedin during childhood in normal subjects and in delayed growth].
Ann Biol Clin (Paris). 1976;34(1):11-8.
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[Somatomedin activity and growth hormone secretion in children with idiopathic growth retardation (author's transl)].特发性生长迟缓患儿的生长调节素活性与生长激素分泌(作者译)
Arch Fr Pediatr. 1980 Oct;37(8):515-9.
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[Blood serum somatomedin activity in children with bone tumors].[骨肿瘤患儿血清生长调节素活性]
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[Circulating somatomedin activity and growth hormone secretion. Changes during late diagnosed celiac disease and effects of treatment].[循环生长介素活性与生长激素分泌。晚发性乳糜泻期间的变化及治疗效果]
Arch Fr Pediatr. 1979 Nov;36(9 Suppl):XIII-XVIII.
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Nutritional intake, somatomedin activity and linear growth in children undergoing hemodialysis.接受血液透析的儿童的营养摄入、生长激素介质活性与线性生长
Proc Clin Dial Transplant Forum. 1976;6:181-3.
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Somatomedin-C/IGF-I measured by radioimmunoassay and somatomedin bioactivity in adolescents with insulin dependent diabetes compared with puberty matched controls.通过放射免疫分析法测定的生长调节素C/胰岛素样生长因子-I以及青少年胰岛素依赖型糖尿病患者的生长调节素生物活性与青春期匹配对照组的比较。
Diabetes Res. 1988 Dec;9(4):177-81.
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Human growth hormone treatment of children with growth failure and normal growth hormone levels by immunoassay: lack of correlation with somatomedin generation.采用免疫分析法对生长发育迟缓但生长激素水平正常的儿童进行人生长激素治疗:与生长调节素生成缺乏相关性。
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[Age- and sex-related variations in the serum concentration of somatomedin C in normal children and adults].[正常儿童和成人血清生长调节素C浓度的年龄和性别相关差异]
Ugeskr Laeger. 1987 May 11;149(20):1320-3.

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