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保留十二指肠的胰头切除术治疗疼痛性慢性胰腺炎

Duodenum preserving resection of the head of the pancreas in painful chronic pancreatitis.

作者信息

Eddes E H, Masclee A A, Lamers C B, Gooszen H G

机构信息

Department of Surgery, University Hospital, Leiden, The Netherlands.

出版信息

Eur J Surg. 1996 Jul;162(7):545-9.

PMID:8874161
Abstract

OBJECTIVE

Evaluation of duodenum preserving resection of the head of the pancreas in patients with disabling pain caused by chronic pancreatitis with an inflammatory mass in the head of the pancreas.

DESIGN

Retrospective study.

SETTING

University hospital. The Netherlands.

SUBJECTS

15 consecutive patients.

MAIN OUTCOME MEASURES

Mortality, morbidity, pain relief, endocrine and exocrine function.

RESULTS

There was no 30 day postoperative mortality. Early morbidity consisted of small bowel leak (n = 1), obstructive ileus (n = 1) and peri anastomotic abscess (n = 2). Relief of pain was achieved in 13 patients (86%) after a mean follow up of 37 months; 11 (73%) were totally free of pain, and 2 (13%) had improved. Neither endocrine nor exocrine function deteriorated significantly after resection.

CONCLUSION

Duodenum preserving resection is an effective operation in patients with disabling pain caused by chronic pancreatitis with an inflammatory mass in the head of the pancreas.

摘要

目的

评估保留十二指肠的胰头切除术治疗慢性胰腺炎伴胰头炎性肿块所致顽固性疼痛患者的疗效。

设计

回顾性研究。

地点

荷兰大学医院。

研究对象

15例连续患者。

主要观察指标

死亡率、发病率、疼痛缓解情况、内分泌和外分泌功能。

结果

术后30天无死亡病例。早期并发症包括小肠瘘(n = 1)、肠梗阻(n = 1)和吻合口周围脓肿(n = 2)。平均随访37个月后,13例患者(86%)疼痛缓解;11例(73%)完全无痛,2例(13%)疼痛改善。切除术后内分泌和外分泌功能均未显著恶化。

结论

保留十二指肠的切除术对于慢性胰腺炎伴胰头炎性肿块所致顽固性疼痛患者是一种有效的手术方式。

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