Lynch M G, Roesch M, Brown R H
Department of Ophthalmology, Emory University, Atlanta, GA, USA.
Ophthalmology. 1996 Oct;103(10):1700-5. doi: 10.1016/s0161-6420(96)30443-0.
To describe a new method of treating large, overfiltering, leaking blebs using a continuous-wave neodymium:YAG laser.
Twenty-three eyes of 23 patients underwent YAG laser remodeling because of overfiltration and hypotony (group 1; n = 14); leaking bleb and hypotony (group 2; n = 5); and large, irritating bleb (group 3; n = 4). Using a neodymium:YAG laser in the continuous-wave multimode, a grid pattern of laser treatment was placed over the entire bleb using energy levels between 3.0 and 4.0 J and a laser offset between 0.9 and 1.2 mm. A torpedo patch then was placed directly over the bleb for 48 hours. Steroid therapy was avoided.
In group 1, 64% of eyes had an intraocular pressure increase of at least 3.0 mmHg. In group 2, 80% of bleb leaks were sealed. In group 3, 100% of patients had resolution of their discomfort. The elevation in intraocular pressure peaked at 1 to 3 months and diminished thereafter. There was improvement in vision of at least two Snellen acuity lines in 52% of eyes. Complications included the need for laser retreatment (7 eyes), creation of temporary bleb leak by the YAG laser (2 eyes), transient increase in intraocular pressure (2 eyes), and corneal edema (1 eye).
The continuous-wave neodymium:YAG laser can be used to effectively change the appearance and behavior of filtering blebs, although the duration of treatment effect is unknown.
描述一种使用连续波钕:钇铝石榴石激光治疗大型、过度滤过、渗漏性滤泡的新方法。
23例患者的23只眼因滤过过度和低眼压(第1组;n = 14);滤泡渗漏和低眼压(第2组;n = 5);以及大型刺激性滤泡(第3组;n = 4)接受了钇铝石榴石激光重塑。使用连续波多模钕:钇铝石榴石激光,在整个滤泡上放置激光治疗网格图案,能量水平在3.0至4.0 J之间,激光偏移在0.9至1.2 mm之间。然后在滤泡上直接放置鱼雷眼罩48小时。避免使用类固醇疗法。
在第1组中,64%的眼睛眼压至少升高3.0 mmHg。在第2组中,80%的滤泡渗漏被封闭。在第3组中,100%的患者不适症状得到缓解。眼压升高在1至3个月达到峰值,此后逐渐下降。52%的眼睛视力至少提高了两行Snellen视力表。并发症包括需要再次进行激光治疗(7只眼)、钇铝石榴石激光造成暂时性滤泡渗漏(2只眼)、眼压短暂升高(2只眼)和角膜水肿(1只眼)。
连续波钕:钇铝石榴石激光可有效改变滤过性滤泡的外观和行为,尽管治疗效果的持续时间尚不清楚。