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单纯疱疹病毒在生殖道的无症状排毒:不确定性及其对患者管理的影响。单纯疱疹病毒咨询小组。

Asymptomatic shedding of herpes simplex virus from the genital tract: uncertainty and its consequences for patient management. The Herpes Simplex Virus Advisory Panel.

作者信息

Barton S E, Munday P E, Patel R J

出版信息

Int J STD AIDS. 1996 Jul;7(4):229-32. doi: 10.1258/0956462961917799.

DOI:10.1258/0956462961917799
PMID:8876351
Abstract

A frequent component of the management of patients with genital herpes concerns the possibility of asymptomatic shedding and potential sexual transmission of the virus. Approaches intended to provide supportive counselling and reassurance of patients about these issues need now to be modified in the light of increasing data of the frequency of asymptomatic detection of virus and the effects of antiviral therapy on this phenomenon. Further studies to delineate the relationship between asymptomatic detection of HSV in the genital tract and the mechanism of sexual transmission of this virus need to be conducted before clinicians instigate antiviral suppressive treatment primarily to prevent sexual transmission of HSV. However, it is important that the new data and our greater understanding of the natural history of genital herpes is translated into accurate and comprehensible information for our patients.

摘要

生殖器疱疹患者管理中的一个常见问题是病毒无症状排毒及潜在性传播的可能性。鉴于越来越多关于病毒无症状检测频率以及抗病毒治疗对该现象影响的数据,现在需要对旨在为患者提供这些问题相关支持性咨询和安慰的方法进行调整。在临床医生主要为预防单纯疱疹病毒(HSV)性传播而开始抗病毒抑制治疗之前,需要进一步开展研究来明确生殖道HSV无症状检测与该病毒性传播机制之间的关系。然而,重要的是要将这些新数据以及我们对生殖器疱疹自然史的更深入理解转化为准确且易于理解的信息传达给我们的患者。

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Asymptomatic shedding of herpes simplex virus from the genital tract: uncertainty and its consequences for patient management. The Herpes Simplex Virus Advisory Panel.单纯疱疹病毒在生殖道的无症状排毒:不确定性及其对患者管理的影响。单纯疱疹病毒咨询小组。
Int J STD AIDS. 1996 Jul;7(4):229-32. doi: 10.1258/0956462961917799.
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引用本文的文献

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Once daily valacyclovir for reducing viral shedding in subjects newly diagnosed with genital herpes.每日一次服用伐昔洛韦以减少初发性生殖器疱疹患者的病毒排出。
Infect Dis Obstet Gynecol. 2009;2009:105376. doi: 10.1155/2009/105376. Epub 2009 Aug 10.
2
Determinants of disclosure of genital herpes to partners.向性伴侣披露生殖器疱疹感染情况的决定因素。
Sex Transm Infect. 2003 Feb;79(1):42-4. doi: 10.1136/sti.79.1.42.
3
British Co-operative Clinical Group national survey on diagnostic issues surrounding genital herpes. MSSVD Special Interest Group on Genital Herpes and the British Co-operative Clinical Group.
英国合作临床小组关于生殖器疱疹相关诊断问题的全国性调查。性传播感染学会生殖器疱疹特别兴趣小组与英国合作临床小组。
Sex Transm Infect. 1999 Dec;75(6):403-5. doi: 10.1136/sti.75.6.403.
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Increasing prevalence of genital herpes in developing countries: implications for heterosexual HIV transmission and STI control programmes.发展中国家生殖器疱疹患病率上升:对异性传播艾滋病毒及性传播感染控制项目的影响
Sex Transm Infect. 1999 Dec;75(6):377-84. doi: 10.1136/sti.75.6.377.
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Genital herpes: review of the epidemic and potential use of type-specific serology.生殖器疱疹:流行病学综述及型特异性血清学的潜在应用
Clin Microbiol Rev. 1999 Jan;12(1):1-8. doi: 10.1128/CMR.12.1.1.