Kuczmierczyk A R, Barbee J G, Bologna N A, Townsend M H
Department of Psychology, City University, London, England.
Can J Psychiatry. 1996 Sep;41(7):465-8. doi: 10.1177/070674379604100712.
To investigate risk for cardiovascular disease in patients with GAD, as well as the effects of comorbid major depression (MD).
Predrug-trial serum cholesterol and triglyceride levels were assessed in 38 patients with pure GAD and compared with those of 21 patients with mixed GAD and comorbid (MD).
Significantly higher cholesterol and triglyceride levels were found in the GAD group.
Increased noradrenergic activity may be responsible for elevations in lipid levels in patients with pure GAD.
研究广泛性焦虑障碍（GAD）患者患心血管疾病的风险，以及共病重度抑郁症（MD）的影响。
对38例单纯GAD患者的用药前血清胆固醇和甘油三酯水平进行评估，并与21例合并GAD和共病MD的患者进行比较。
GAD组的胆固醇和甘油三酯水平显著更高。
去甲肾上腺素能活性增加可能是单纯GAD患者血脂升高的原因。
