Matthews R, Burnie J
University Dept of Medical Microbiology, Manchester Royal Infirmary, UK.
Trends Microbiol. 1996 Sep;4(9):354-8. doi: 10.1016/0966-842x(96)10056-1.
For many years, there has been controversy over the role of antibodies in immunity to Candida, but recently specific antibodies to mannoproteins and hsp90 have been shown to be protective against murine candidiasis. Combined with technical advances in antibody engineering, this raises the possibility of harnessing such antibodies into a new range of therapeutics.
多年来，关于抗体在抗念珠菌免疫中的作用一直存在争议，但最近已证明针对甘露糖蛋白和热休克蛋白90的特异性抗体对小鼠念珠菌病具有保护作用。结合抗体工程技术的进步，这增加了将此类抗体应用于一系列新疗法的可能性。
