McRae D, Young P, Hamilton J, Jones A
University Department of Otorhinolaryngology/Head and Neck Surgery, Royal Liverpool Hospital, UK.
Clin Otolaryngol Allied Sci. 1996 Aug;21(4):366-8. doi: 10.1111/j.1365-2273.1996.tb01089.x.
The physiological airflow resistance from the anterior nares to the upper trachea has recently been documented. This resistance is thought to be important in preventing alveolar collapse and in maintaining the optimum lung ventilation: perfusion ratio. This resistance is lost in laryngectomees who may have a subsequent decline in lung function and arterial oxygen saturation. A stoma filter with a resistance approximating to that of the normal upper airway has been developed and laryngectomees who wear this device demonstrate a rapid increase in tissue oxygen saturation (median increase: 1.4 kPa, P = 0.0087) without significantly altering tissue carbon dioxide saturation. This finding will have a major impact on the future rehabilitation of laryngectomees and those with a temporary tracheostomy.
最近已记录了从前鼻孔到上气管的生理气流阻力。这种阻力被认为在防止肺泡塌陷和维持最佳肺通气：灌注比方面很重要。这种阻力在喉切除患者中丧失，这些患者随后可能出现肺功能和动脉血氧饱和度下降。已开发出一种阻力近似于正常上呼吸道阻力的造口过滤器，佩戴该装置的喉切除患者组织氧饱和度迅速增加（中位数增加：1.4 kPa，P = 0.0087），而组织二氧化碳饱和度无明显变化。这一发现将对喉切除患者和临时气管切开患者的未来康复产生重大影响。
