Korzenik J R
Section of Digestive Diseases, Yale School of Medicine, New Haven, CT 06520, USA.
Gastroenterologist. 1996 Sep;4(3):203-10.
Vascular lesions in the gastrointestinal tract have been increasingly recognized as important causes of bleeding. Patients with bleeding gastric and small bowel vascular ectasia often pose difficult diagnostic and management problems; they require numerous transfusions, repeated hospital admissions, and multiple endoscopic procedures. With improving endoscopic options and emerging medical therapies, management of these patients is changing. This set of disorders requires a variety of approaches tailored to the particular disorder and clinical manifestations. Hereditary hemorrhagic telangiectasia (HHT) is a disorder that can involve multiple organ systems outside the gastrointestinal tract in a variety of clinical presentations. Screening all patients with HHT for pulmonary and cerebral arteriovenous malformations to prevent significant sequelae is a critical element of care. This review focuses on advances in our knowledge and treatment of HHT and other gastric and small intestinal vascular ectasia.
胃肠道血管病变已日益被视为出血的重要原因。胃和小肠血管扩张症出血的患者常常面临诊断和管理难题；他们需要多次输血、反复住院以及多次内镜检查。随着内镜选择的不断改进和新兴药物疗法的出现，这些患者的管理正在发生变化。这组疾病需要根据特定疾病和临床表现采取多种方法。遗传性出血性毛细血管扩张症（HHT）是一种可累及胃肠道以外多个器官系统、具有多种临床表现的疾病。对所有HHT患者进行肺和脑动静脉畸形筛查以预防严重后遗症是护理的关键环节。本综述重点关注我们在HHT以及其他胃和小肠血管扩张症的认识和治疗方面的进展。
