2,5-Hexanedione induced apoptosis in cultured mouse DRG neurons.

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作者信息

Ogawa Y, Shimizu H, Kim S U

机构信息

Department of Public Health and Environmental Medicine, Jikei University School of Medicine, Tokyo, Japan.

出版信息

Int Arch Occup Environ Health. 1996;68(6):495-7. doi: 10.1007/BF00377875.

DOI:10.1007/BF00377875

PMID:8891791

Abstract

摘要

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2,5-Hexanedione induced apoptosis in cultured mouse DRG neurons.

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本文引用的文献

The relative neurotoxicity of methyl-n-butyl ketone, n-hexane and their metabolites.甲基正丁基甲酮、正己烷及其代谢产物的相对神经毒性。

Toxicol Appl Pharmacol. 1980 Mar 15;52(3):433-41. doi: 10.1016/0041-008x(80)90338-5.

In vitro evidence that covalent crosslinking of neurofilaments occurs in gamma-diketone neuropathy.体外证据表明神经丝的共价交联发生在γ-二酮神经病中。

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Further observations on in vitro and in vivo effects of 2,5-hexanedione on glyceraldehyde-3-phosphate dehydrogenase.关于2,5 -己二酮对3 -磷酸甘油醛脱氢酶的体外和体内作用的进一步观察

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Toxic polyneuropathy produced by methyl N-butyl ketone.甲基正丁基甲酮引起的中毒性多发性神经病。

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Alterations in rat axonal cytoskeletal proteins induced by in vitro and in vivo 2,5-hexanedione exposure.体外和体内暴露于2,5 -己二酮所诱导的大鼠轴突细胞骨架蛋白的改变。

Toxicol Appl Pharmacol. 1985 Apr;78(2):235-47. doi: 10.1016/0041-008x(85)90287-x.

Uncoupling of cerebral glucose supply and utilization after hexane-2,5-dione intoxication in the rat.大鼠己烷-2,5-二酮中毒后脑葡萄糖供应与利用的解偶联

J Neurochem. 1987 Mar;48(3):816-23. doi: 10.1111/j.1471-4159.1987.tb05590.x.

Comparative neurotoxicity and pyrrole-forming potential of 2,5-hexanedione and perdeuterio-2,5-hexanedione in the rat.2,5-己二酮和全氘代-2,5-己二酮在大鼠体内的比较神经毒性及形成吡咯的潜力

Toxicol Appl Pharmacol. 1988 Jan;92(1):75-85. doi: 10.1016/0041-008x(88)90229-3.

Pyrrole oxidation and protein cross-linking as necessary steps in the development of gamma-diketone neuropathy.吡咯氧化和蛋白质交联是γ-二酮神经病发展过程中的必要步骤。

Chem Res Toxicol. 1988 May-Jun;1(3):179-85. doi: 10.1021/tx00003a009.

2,5-Hexanedione is a potent gliatoxin in in-vitro cell cultures of the nervous system.2,5 -己二酮是神经系统体外细胞培养中的一种强效神经胶质毒素。

Neurotoxicology. 1992 Spring;13(1):151-4.

Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation.通过核DNA片段化的特异性标记原位鉴定程序性细胞死亡。

J Cell Biol. 1992 Nov;119(3):493-501. doi: 10.1083/jcb.119.3.493.

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